Background: IUDs are very safe and highly effective methods of contraception that can be used at anyrnpoint of the menstrual cycle and postpartum. They can also be used as an emergency contraception. Allrnthese benefits should make them the preferred choice amongst clients. Further data is needed...
Background: Hypertension (HTN) is one of the key preventable causes of morbidity and mortalityrnworldwide if it is not detected early and treated appropriately. The prevalence rate of hypertensionrnis on the rise in developing countries with no improvement in awareness and blood pressure...
Background: Diabetes mellitus (DM) is a group of metabolic disorders of fat, carbohydraternand protein metabolism that results from defects in insulin secretion, action, or both. About 50%rnchronic care patients in the developed countries are non-adherent and it is estimated to be higherrnin...
Introduction: Clinical trial is an extensive and demanding process, which takes approximatelyrn10 to 15 years. Clinical trials require the active engagement of human subjects. Recruitment andrnretention of participants are two major challenges in conducting clinical trials. Poor recruitmentrnand...
Card banking customer in Ethiopia faces the problem of identifying nearby active ATM service.rnResearch shows that more than 50% of card banking customers are unsatisfied with the existingrncard banking service at their respective banks in Ethiopia. The aim of this study is to explore andrndesign...
An ecological study of Salt’s dik-dik was conducted during July 2017-August 2019. The study was aimed investigating the population size, habitat association, diurnal time budget and diet composition of the animal. In addition, conservation challenges and opportunities rooting from the local...
Background: Evaluation of the interchangeability of multi-source generic drug products or bioequivalencernrnstudy has become a crucial activity since the share of generic medicines inrnhealthcare has enormously grown over the past few decades. Among four East African Countries,rnrnnamely, Ethiopia,...
Background: Medical products are regulated from premarket clinical trials to post marketingrnsurveillance and phase IV clinical trials. Research organizations have responsibilities to conductrnclinical trials subject to regulatory and national ethics review process before putting products onrnthe...
Background: The emergence and resurgence of zoonotic diseases have continued to be arnmajor threat to global health and the economy. Developing countries are particularlyrnvulnerable due to agricultural expansions and domestication of animals with humans.rnScientifically sound clinical trials are...
Background :rnAntibiotic-resistant pathogens constitute an important and growing threat to public health. The emergencernof multidrug-resistant organisms in nosocomial infections is being highly associated with frequent causesrnof morbidity and mortality in patients. In view of the growing threat...
Introduction: A clinical trial is a research method used to provide evidence on the safety andrneffectiveness of interventions for specific medical conditions. In contrary to the disease burden,rnmost of the clinical trials were conducted in developed countries and the share of Africa as of...
Background: Schistosomiasis is a parasitic disease caused by worms of the genus Schistosoma.rnAlmost 85% of infected individuals live in Africa. Infection among preschool-aged children (1-5rnyears) in endemic areas was underestimated and is currently excluded from preventivernchemotherapy because...
Background: Integrase strand transfer inhibitors (InSTIs) are the most recent class of drugsrnapproved on the basis of their efficacy and safety profiles (16). Dolutegravir and elvitegravir arernconsidered US Food and Drug Administration pregnancy category B; while raltegravir belongsrnto category...
Background: Otitis media is an ear infection middle that caused by bacteria or a viruses, whichrnaffects more children. Amoxicillin/clavulanate is the drug of choice for otitis media currently.rnHowever emergency of resistance, long duration of treatment and more adverse reactions makernamoxicillin...
Background: The benefits of combination therapies in the management of type 2 diabetes arernwell-documented, while the comparative glycemic control and cardiovascular outcomes amongrnthe different combination options have not been studied well. The study aimed to comparernglycemic control and risk...
Background and Objectives: Although the goal of translational research is to bring biomedicalrnknowledge from the laboratory to clinical trial and therapeutic products for improving health, thisrngoal has not been well achieved as often as desired because of many barriers documented inrndifferent...
Background: Visceral leishmaniasis is among the most neglected tropical infectiousrndisease caused by the protozoan parasite of the genius lesihmania. The incidence of VL isrnestimated to be 0.2 to 0.4 million cases /year worldwide. It is fatal if left untreated. rnObjective: The objective of this...
Interferon-γ release assays (IGRAs) such as QFT gold plus is one of the main toolsrnfor the diagnosis of latent TB infection (LTBI). The main objective this study was tornassess the effect of Rifapentin and Isoniazid (3HP) on IGRA reversion andrnconversion. rnIGRA reversion and conversion rates...
Respiratory rate problem is the major reason of morbidity and mortality in infancy and childhood which has a long-term impact on health outcomes in adult life. The main objective of the study was identifying risk factors associated with preterm infant respiratory rate. Secondary data was taken from...
This paper sets out to explore the economy wide effects of Ethiopia's measure to liberalize itsrnagricultural trade according to the rules of EPA (Economic Partnership Agreement). Thisrnobjective is undertaken by highlighting 011 sectoral and macroecollomic indicators. To this end,rnthe dy"amic...