Evaluation Of Antihyperglycemic Effect Of Moringa Stenopetala Aquoeous Leaves Extract On Alloxan Induced Diabetic Rats

Background: Diabetes is a serious metabolic disorder with complications that results inrnsignificant morbidity and mortality. Current drugs used for diabetes therapy are not freernfrom side effects and do not restore normal glucose homeostasis. Therefore, the purpose ofrnthis study is to evaluate antidiabetic, and pancreatic damage effect of Moringa stenopetalarnaqueous extract on alloxan induced diabetic rats.rnMethods:-The aqueous extract of Moringa stenopetala leaves 250 and 500mg/kg andrnGlibenclimide 5mg/kg/ body weight were administered to alloxan induced diabetic rats.rnAll were administered orally using intragastric gavage for 28 days. Blood glucose level,rnHistopathological examination, liver and kidney functions, preliminary phytochemicalrnscreening tests were done.rnResult:-After IP administration of Alloxan monohydrate, the fasted blood glucose levelrnrose in all experimentally induced diabetic groups. Administration of M. stenopetala leavesrnaqueous extract to diabetic rats showed remarkably reduction in blood glucosernconcentration, there were significant (P

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