Phytochemical Investigation On The Aerial Part Of Anthemis Tigreensis (chloroform Extract)

A. tigreensis in the family Asteraceae, in the genus Anthemis is the only species found in Ethiopia.rnA. tigreensis has medicinal value and is important in traditional medicine like the other species in therngenus. Anthemis nobilis (Chamomile) has been known from Roman times as an antispasmodic andrnsedative in folk treatment of digestive and rheumatic disorders. It is also a popular herb tea. A. cotularnshows antimicrobial activity against both Gram-negative and Gram-positive microorganisms. Inrnlocal medicine, the roots of A.tigreensis are used against wet eczema.rnIn this work, two compounds, At-3(AntheindurolideA) and At-17(dihydro-5-(4-(tetrahydro-3-rnmethylene-2-oxofuran-4-yl)-2-hydroxy-2-methylbut-3-enyl)-3-methylfuran-2(3H)-one were isolatedrnfrom the aerial part of the plant. At-3 was isolated before from A. tigreensis and other species ofAnthemis. To the best of our knowledge compound At-17 has not been reported before in theNatural Product Dictionary and literature. The structures were elucidated from 1D and 2D-NMR,UV and IR spectra data and by comparison of the data obtained with those reported for thecompounds in the literature.

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