Adoptive Transfer Of Lymphocytes And Its Role In Protection Against Schitosoma Mansoni Infection In Arvicanthus Species

Adoptive transfe r o f pr o t f!c tio n f rom i nf 'ctcd don orrnJ.rvicanthus !.E. rats t o uninfec t ed r c cl pient~ was t!l ttt!mptedrnby va ~ y ing s omc pilram ~~b.! rs such a s the i ntl:ction pe riod o frndonor r ats a nd the tine of tra ns f L; r r e l ati ve to c ha l ll.;nge .rnConcurre nt inve stigation o n t he e ffect of h~'~ r o l o g ousrninfec tion and fra ctio na tion o f c e ll s 11(l!:; ~lso carri(:d out.rnIt wa s f ound tha t cPlls from 2 mo n th- lnfLctcd dono rs hadrnhigh ability t o tra n s f c r r e sista ncl.! to rc:d,p i €..nt r atsrnwhile c el ls f r om 10 75 a nd 3 month- infL:ctcc' Jonor s s howedrnpa rtial a bi l ity and tho s e fr om 2 . 5 mo nth- infl:ctcd donorsrnshowed an une xpe cted inhi b i t ory e f fect on t ransfe rrnr e cipi e nts. Transfe rs d o ne c l o s e t o ch a ll L:ng~ nay c onfe rrnalmo s t c omple t e i mmunity t o r e cipie nt rats , 0,:.':"_rnHeterologous c e stode infe ction in t hes(! r-~ts appt:"!

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