Background: Malignant laryngeal tumors are uncommon, yet invariably fatal neoplasms ofrnthe larynx. Late presentation of the disease may worsen management outcomes. Although thernincidence of malignant tumors of the larynx is increasing in developing countries, like Ethiopia,rnthere is a lack of evidence regarding the overall profile of laryngeal cancers in Ethiopia. rnObjectives: To assess the epidemiologic, clinico-histo-pathologic characteristics of laryngealrnpatients attending at oncology department of Tikur Anbessa Specialized Hospital, AddisrnAbaba, Ethiopia.rnMethods: A 3-year retrospective cross-sectional review of medical records of patientsrnmanaged for malignant laryngeal tumors at the oncology department of Tikur AnbessarnSpecialized Hospital, Addis Ababa, Ethiopia, was performed. The demographic, clinical &rnhistopathologic characteristics of participants were computed by using descriptive statisticsrn(mean, percentage, frequencies, and standard deviation). Finally, the study finding wasrnpresented using diagrams, tables, and figures. rnResults: Most of the laryngeal cancer patients who attended the oncology unit of TikurrnAnbessa Specialized Hospital are elderly males, with a male to female ratio of 5.1:1, and thernsixth decade being the most affected age stratum. The most common presenting symptom wasrndysphonia. The majority (88.8%) of patients presented with late stage of the disease andrnsquamous cell carcinoma is by far the most common histopathology, occurring in 98.8% of thernpatients.rnConclusion: Elderly men are the most affected age group of laryngeal neoplasms. Late diseasernpresentation observed in the patients can lead to poor management outcomes and limitedrnmanagement options. Health education of the community on early features of laryngeal cancer,rnearly symptom detection by clinicians, and policies targeted at reducing cigarette smoking andrnalcohol consumption is recommended.