Background: Nursing Process is a systematic problem-solving approach used to identify, preventrnand treat actual or potential health problems and promote wellness. It has five steps- assessment,rndiagnosis, planning, implementation, and evaluation.rnObjective: To assess factors affecting implementation of nursing process among nurses inrnselected governmental hospitals of Addis Ababa.rnMethod: A cross-sectional study was conducted on selected governmental hospitals in AddisrnAbaba from February-April, 2011. Both quantitative and qualitative methods were used.rnPurposive sampling was used for selection of hospitals. Black Lion, St. Paul, Ras Desta DamitewrnMemorial, and Yekatit 12 hospitals were convenient for the study. The participants were selectedrnusing simple random sampling technique. The minimum sample size was 202. Tools were givenrnto nurse expatriate to check for its validity and adjustment was made according to the feedbackrnobtained before pre test. Data was collected using self-administered questionnaire and in-depthrninterview. Data was analyzed using SPSS 16th version.rnResult: Out of 202 sampled respondents 192 agreed to participate in the study and the responsernrate was 95%. One hundred two (53.1%) were females and 90(46.9%) were males. One hundredrnforty (72.9%) of the total respondents were working in a stressful working environment where asrn31(16.1%) were working in a disorganized working environment, the remaining 21(10.9%)rnrespondents explained their work place was negligent at a time.rnThirty one (16.1%) ofrnrespondents were highly knowledgeable. From the total respondents 89(46.4%) were highlyrnskillful. One hundred (52.1%) of respondents have implemented nursing process. From binaryrnlogistic regression model analysis those who have implemented nursing process were nursesrnworking in a stressful working environment were 2.8(adjusted OR: 0.357, 95%CI: (0.157-0.814)rntimes less likely to implement nursing process than disorganized working environment adjustingrnfor facility accessibility, knowledge, and sex. Accessibility of facilities needed for nursing carernwere 2.248(Adjusted OR: 2.248, 95%CI: (1.079-4.684))times more likely to implement nursingrnprocess than nurses working in an inferior facility controlling for working environment,rnknowledge, and sex. Highly knowledgeable respondents were 38.913(Adjusted OR: 38.913,rn95%CI: (10.3-147.006))times more likely to implement nursing process than low knowledgerngroup nurses adjusted for working environment, facility, and sex.rnConclusion: Nursing process implementation is affected by various factors. The study hasrnidentified organizational factors, patient related factors, and level of knowledge and skill werernamong those factors highly influenced nursing process implementation. This factors cause poorrnquality of nursing care, disorganized caring system, conflicting role, medication error andrnreadmission with similar problem, dissatisfaction with the care patients have received, andrnincreased mortality.