Assessment Of Coagulation Profile Among Adult Cardiac Outpatient Department Of Tikur Anbessa Hospital Addis Ababa Ethiopia.

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Background; the coagulation process is initiated by platelets forming a plug at the location ofrnthe injury within few seconds of a breach in the vascular integrity. This constitutes the primaryrnhaemostatic mechanism. Secondary homeostasis is a multifaceted interaction between plasmarncoagulation factors, which results in the creation of fibrin strands strengthening the platelet plug.rnA hospital based cross sectional (retrospective chart review) study design was employed andrnsimple random sampling techniques was used. Sample size is calculated by taking assumptionsrnof 95% confidence level, there is no other study conducted related with this title to being use as arnreference proportion so I took 50% (P=0.5) as a reference proportion. And adding 10 % nonrespondentsrnrate.rnTherntotalrnpopulationrnunderrnstudy,rnwhichrnmeansrntotalrnpatientrnnumberrnwhornattendrnrncardiacrnrnclinic in last month, was 1000 so by using correction formula the sample size becomesrn306. rnIn this study we found that the mean INR value of a patient under study was 3.037 (SD: ±1.43)rnand the median was 2.9.While the quarantines was 2.0 – 3.65. According to our study, the datarnconfirmed that the mean platelet count of the study unit was 282248(SD: ±89589). However, thernmean PTT value of patients was 41.7 seconds (SD: ±11seconds). While the minimum PTT wasrn22 seconds and the maximum was 77 seconds. as this study is hospital based with limitedrnrepresentativeness population based studies are recommended.

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Assessment Of Coagulation Profile Among Adult Cardiac Outpatient Department Of Tikur Anbessa Hospital Addis Ababa Ethiopia.

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