Background: The prevalence of H. pylori infection mainly acquired during childhood andrnmay be persisting throughout life and it has been found high in developing countries; thisrnprevalence is related to low socioeconomic status, and Intestinal parasitic infections arernamong the major public...
Background: Surgical wound infection is a prototype of (Hospital Acquired Infection) HAIrnand constitutes a serious problem. Patients diagnosed with Surgical Site Infection (SSI) face a 2rnto 11 times increased in mortality along with prolonged hospital stays, treatment associated risks,rnculture...
Background; Medical laboratory services are an essential component of health systems.rnStrengthening these services can combat the major infectious diseases. Laboratory accreditationrnsystem is found to be essential to have national and international acceptance of variousrnlaboratory test results....
Diabetes mellitus is a major public health problem in the world. The prevalence ofrndiabetes mellitus is increasing with ageing of the population and lifestyle changesrnassociated with rapid urbanization and westernization. According to the WorldrnHealth Organization estimate 3% of the...
Malaria is a major public health problem mainly due to the development of drug resistancernby the most lethal causative parasitic species. New drugs with unique structures andrnmechanism of action are urgently required to treat sensitive and drug-resistant strains ofrnmalaria. Historically,...
Malaria and leishmaniasis are the most prevalent tropical diseases caused by protozoan parasites.rnHalf of world's population is at risk of malaria and more than 2 million of new cases ofrnleishmaniasis occur annually. There are no effective vaccines available for these diseases andrncurrent...
ITNs are widely promoted as means of preventing man- vector contact in the control of malaria.rnDevelopment of Long Lasting Insecticidal Nets (LLINs) avoids the need for re-treatment which was arnmajor operational problem faced by net owners. There are, however several factors which affect...
In this work, some derivatives of 2-pyrazolyl-4(3H)-quinazolinones have been synthesized byrncyclization and condensation reactions. The synthesized compounds were obtained in a goodrnyield (55.9-94%). The chemical structures of the final compounds were also verified byrnspectroscopic tools (IR, 1H...
Background: The association of obesity with development of type 2 diabetes may bernpartly mediated by altered secretion of adipokines by adipose tissue. Greater adiposityrndown regulates secretion of adiponectin, an adipokine with anti-inflammatory and insulinrnsensitizing properties. The strength...
Background: Breast cancer has become a major public health problem in developing regions, asrnincidence rate is particularly growing in these regions of the world. Oxidative damage andrnmodification of biomolecules including proteins, lipids and DNA can increase the risk ofrnmutagenesis. It has...
Background: Interest in the physiological role of bioactive compounds present in plants hasrnincreased dramatically over the last decade. Of particular interest in relation to human health arernthe classes of compounds known as the phytoestrogens, which include several groups of non-rnsteroidal...
Background: Cigarette butts are the most common form of litter in the world;rnapproximately 5.6 trillion cigarettes are smoked yearly worldwide. Over 7000 chemicalsrnmay be introduced to the environment in cigarette butts and smoke constituents. Theserninclude chemicals such as nicotine, carbon...
Introduction: Obesity results from environmental and genetic factors and is rapidlyrngrowing public health problem with its leading co-morbidity type 2 diabetes. Greatrnemphasis has been put on establishing treatments for obesity, including pharmacologicalrnintervention using animal models of...
Background: Nonalcoholic fatty liver disease is one of the most common causes ofrnchronic liver disease in the Western world, and it‟s likely to parallel the increasingrnprevalence of type 2 diabetes, obesity, and other components of metabolic syndrome.rnThere is also growing evidence in both...
Back ground: Tea is the second widely consumed drink in the world next to water and used byrnpeople in different parts of the world for treatment of different health ailments; especially, green tea.rnHAART which is a recently(since 1996) developed form of ART medication to treat HIV/AIDS isrnnow...
Introduction: Malaria is one of the world’s most serious infectious diseases caused byrnPlasmodium parasites. An increased drug resistance to conventional anti-malarial,rnincreasing resistance of mosquito vectors to insecticides, challenge of having effectivernvaccines and adverse effects of...
Breast cancer is the most frequent cause of cancer death in women in less developed countriesrnincluding Ethiopia. Cellular proteases thought to increase the likelihood of cancer invasion andrnmetastasis by degrading components of extracellular matrix. These proteases could be used asrntumor...
Objective: To assess the association between serum magnesium levels and risk of type 2 diabetesrnand to evaluate the effect of magnesium supplementation on diabetes status.rnDesign: Systemic reviewrnData Sources: By the electronic databases searches journals and retrieved studies published...
Back ground: Depo-medroxyprogesterone Acetate (DMPA) is a long acting, injectablernprogesterone derivative contraceptive which is currently used by more than 90 million womenrnworldwide, including Ethiopia. This contraceptive is suggested to induce changes in lipid profile,rnbody weight and blood...
The augmented block design is widely used in breeding programs, particularlyrnin screening and selection of a large number of germplasm lines with non-replicatedrntest treatments and replicated control treatments to estimate the experimental error. Thernstudy establishes a relationship between...