Postgraduate Project Topics, Thesis and Dissertation

23201 Prevalence Of Helicobacter Pylori And Intestinal Parasite And Their Associated Risk Factors Among School Children At Selam Fire Elementary School In Akaki Kality Addis Ababa Ethiopia

Background: The prevalence of H. pylori infection mainly acquired during childhood andrnmay be persisting throughout life and it has been found high in developing countries; thisrnprevalence is related to low socioeconomic status, and Intestinal parasitic infections arernamong the major public...

23202 Incidence Of Surgical Site Infection Predisposing Factors And Associated Costs At Dessie Referral Hospital Dessie Ethiopia

Background: Surgical wound infection is a prototype of (Hospital Acquired Infection) HAIrnand constitutes a serious problem. Patients diagnosed with Surgical Site Infection (SSI) face a 2rnto 11 times increased in mortality along with prolonged hospital stays, treatment associated risks,rnculture...

23203 Assessing The Outcome Of Strengthening Laboratory Management Towards Accreditation (slmta) On Laboratory Quality Management System In City Government Of Addis Ababa.

Background; Medical laboratory services are an essential component of health systems.rnStrengthening these services can combat the major infectious diseases. Laboratory accreditationrnsystem is found to be essential to have national and international acceptance of variousrnlaboratory test results....

23204 Antidiabetic Activity And Phytochemical Screening Of Crude Extracts Of Stevia Rebaudiana Bertoni And Ajuga Remota Benth Grown In Ethiopia On Alloxan-induced Diabetic Mice

Diabetes mellitus is a major public health problem in the world. The prevalence ofrndiabetes mellitus is increasing with ageing of the population and lifestyle changesrnassociated with rapid urbanization and westernization. According to the WorldrnHealth Organization estimate 3% of the...

23205 In Vivo Antimalarial Evaluation Of Embelin And Some Semi- Synthetic Aromatic Amine Substituted Embelin Derivatives From The Fruit Of Embelia Schimperia

Malaria is a major public health problem mainly due to the development of drug resistancernby the most lethal causative parasitic species. New drugs with unique structures andrnmechanism of action are urgently required to treat sensitive and drug-resistant strains ofrnmalaria. Historically,...

23206 Synthesis Of Some Novel 2-styryl-4(3h)-quinazolinone Derivatives With Potential Antimalarial And Antileishmanial

Malaria and leishmaniasis are the most prevalent tropical diseases caused by protozoan parasites.rnHalf of world's population is at risk of malaria and more than 2 million of new cases ofrnleishmaniasis occur annually. There are no effective vaccines available for these diseases andrncurrent...

23207 Evaluation Of Wash Resistance Of Longlastng Insecticidal Nets Currently Available In Ethiopia And Comparison With Conventionally Treated Nets

ITNs are widely promoted as means of preventing man- vector contact in the control of malaria.rnDevelopment of Long Lasting Insecticidal Nets (LLINs) avoids the need for re-treatment which was arnmajor operational problem faced by net owners. There are, however several factors which affect...

23208 Synthesis Of Some Novel 2-pyrazolyl-4(3h)-quinazolinone Derivatives With Potential Antimalarial And Antileishmanial Activities

In this work, some derivatives of 2-pyrazolyl-4(3H)-quinazolinones have been synthesized byrncyclization and condensation reactions. The synthesized compounds were obtained in a goodrnyield (55.9-94%). The chemical structures of the final compounds were also verified byrnspectroscopic tools (IR, 1H...

23209 The Involvement Of Adiponectinin Type 2 Diabetesa Systematic Review Of Findings Onhuman

Background: The association of obesity with development of type 2 diabetes may bernpartly mediated by altered secretion of adipokines by adipose tissue. Greater adiposityrndown regulates secretion of adiponectin, an adipokine with anti-inflammatory and insulinrnsensitizing properties. The strength...

23210 Investigation Of Serum Markers Of Oxidative Stress Among Breast Cancer Patients In Tikur Anbessa Specialized Teaching Hospital Addis Ababa Ethiopia

Background: Breast cancer has become a major public health problem in developing regions, asrnincidence rate is particularly growing in these regions of the world. Oxidative damage andrnmodification of biomolecules including proteins, lipids and DNA can increase the risk ofrnmutagenesis. It has...

23211 A Systemic Review On Effects Of Phytoestrogen On Breast Cancer

Background: Interest in the physiological role of bioactive compounds present in plants hasrnincreased dramatically over the last decade. Of particular interest in relation to human health arernthe classes of compounds known as the phytoestrogens, which include several groups of non-rnsteroidal...

23212 Investigation Of Toxicity Of Cigarette Butts Collected In Addis Ababa To Swiss Albino Mice

Background: Cigarette butts are the most common form of litter in the world;rnapproximately 5.6 trillion cigarettes are smoked yearly worldwide. Over 7000 chemicalsrnmay be introduced to the environment in cigarette butts and smoke constituents. Theserninclude chemicals such as nicotine, carbon...

23213 Effect Of Resveratrol Metformin And Eucalyptus Oil On Visceral Fat Deposition Serum Glucose Lipid Profiles And Liver Function Tests Of Swiss Albino Mice Fed A High-fat Diet

Introduction: Obesity results from environmental and genetic factors and is rapidlyrngrowing public health problem with its leading co-morbidity type 2 diabetes. Greatrnemphasis has been put on establishing treatments for obesity, including pharmacologicalrnintervention using animal models of...

23214 Hepatoprotective Effect Of Silymarin On Fructose Induced Nonalcoholic Fatty Liver Disease In Male Albino Wistar Rats

Background: Nonalcoholic fatty liver disease is one of the most common causes ofrnchronic liver disease in the Western world, and it‟s likely to parallel the increasingrnprevalence of type 2 diabetes, obesity, and other components of metabolic syndrome.rnThere is also growing evidence in both...

23215 Effect Of Green Tea (camellia Sinensis) Leaf Extract On Highly Active Anti- Retroviral Therapy Induced Dyslipidemia And Non Alcoholic Fatty Liver Disease In Albino Wistar Rats

Back ground: Tea is the second widely consumed drink in the world next to water and used byrnpeople in different parts of the world for treatment of different health ailments; especially, green tea.rnHAART which is a recently(since 1996) developed form of ART medication to treat HIV/AIDS isrnnow...

23216 Invivo Anti-malarial Evaluation Of Leaf Extract Of Vernonia Amygdalina Del. (asteraceae) Against Plasmodium Berghei

Introduction: Malaria is one of the world’s most serious infectious diseases caused byrnPlasmodium parasites. An increased drug resistance to conventional anti-malarial,rnincreasing resistance of mosquito vectors to insecticides, challenge of having effectivernvaccines and adverse effects of...

23217 Zymographic Detection And Clinical Correlations Of Cysteine Cathepsin And Matrix Metalloproteinase In Human Breast Cancer Tissue

Breast cancer is the most frequent cause of cancer death in women in less developed countriesrnincluding Ethiopia. Cellular proteases thought to increase the likelihood of cancer invasion andrnmetastasis by degrading components of extracellular matrix. These proteases could be used asrntumor...

23218 Serum Magnesium Level And Magnesium Supplementation On Type 2 Diabetes Mellitus Systematic Review

Objective: To assess the association between serum magnesium levels and risk of type 2 diabetesrnand to evaluate the effect of magnesium supplementation on diabetes status.rnDesign: Systemic reviewrnData Sources: By the electronic databases searches journals and retrieved studies published...

23219 Effects Of Depo-medroxyprogesterone Acetate (dmpa) On Lipid Profile Body Weight And Blood Pressure Among Women In Tekele Hymanot And Lomeda Health Centers Addis Ababa Ethiopia

Back ground: Depo-medroxyprogesterone Acetate (DMPA) is a long acting, injectablernprogesterone derivative contraceptive which is currently used by more than 90 million womenrnworldwide, including Ethiopia. This contraceptive is suggested to induce changes in lipid profile,rnbody weight and blood...

23220 Construction And Analysis Of Augmented And Modified Augmented Designs

The augmented block design is widely used in breeding programs, particularlyrnin screening and selection of a large number of germplasm lines with non-replicatedrntest treatments and replicated control treatments to estimate the experimental error. Thernstudy establishes a relationship between...

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