Background:Arrhythmia is a condition in which the heart beats become abnormal rhythms, below60 or above 100 beats per minute. Arrhythmias are common clinical events in the intensive care unit(ICU) setting, including COVID-19 patients. A global survey indicates that there is a higher inci-dence of arrhythmia in COVID-19 patients that accounts for 16.8% of their deaths, and reports 2deaths out of 10 after developing arrhythmia.Objective:The study's goal is to assess the prevalence of arrhythmias and associated factors in CO-VID-19 patients in the ICU at public COVID-19 treatment centers in Addis Ababa, Ethiopia.Method:A descriptive cross-sectional study design based on a facility was used. A simple randomsampling technique was used to select the records of 422 patients whose records fulfilled the inclu-sion criteria from February 15, 2021, until April 15, 2021, in Addis Ababa. A checklist was preparedto collect the data. The statistical software SPSS Version 26.0 was used to collect, enter, and analyzethe data. The ethical clearance was obtained from Addis Ababa University College of HealthSciences, School of Nursing and Midwifery. The frequency, median, and standard interquartile rangewere calculated using descriptive statistics and inferential statistics such as bivariate and multivaria-ble logistic regression analysis; statistical significance was determined using a P-value less than0.05.The results were presented using tables and charts.Result:The result showed that most of the study subjects were in the age range of 62â€“76 years old.The median age of the study population was 60 (interquartile range 50-70) years. Among the total422 patientâ€™ records analyzed, 270 (64%) of them were males. The prevalence of cardiac arrhyth-mias was 231 (54.7%). Patients aged (16-31) [AOR = 0.24; 95%CI (0.084-0.678)], those aged (32-46) [AOR = 0.106-0.766]], those with a history of CKD [AOR = 0.155; 95%CI (0.035-0.690)], andthose with high serum Cl-[AOR = 3.88; 95%CI (1.17-12.85)] were found to have a significant asso-ciation.(p < 0.05, 95% C. I).Conclusion:The majority of COVID-19 patients admitted to the ICU had cardiac arrhythmias. Arr-hythmia prevalence is associated with serum Cl imbalance.