The Paper seeks to examine the effect of knowledge management on organizational performance in Panafric Global plc. The study specifically sets out to determine a significant relationship between the knowledge management process and organizational performance. It also examines the extent to which knowledge management factors affect the performance of an organization. The target population of this research was 116 employees. The researcher used the probability sampling technique, which is simple random sampling, for distributing the questionnaire. The study used descriptive and explanatory survey research design. The approach used in this research is quantitative approaches. The studyâ€™s primary data were collected through a questionnaire, and it is the major resource for this study. Then, descriptive statistical methods, multiple regression, Multicollinearity test and Pearson correlation analysis were used, and results would be presented. The findings of this study show that processes and factors of knowledge management, except organizational structure, were not practiced in the organization, the existence of a significant positive relationship between the knowledge management process and organizational performance. It also reveals that knowledge management factors have a positive effect on organizational performance. Therefore, the study concludes that knowledge management processes and knowledge management factors affect organizational performance. Thus, the researcher recommends that Panafric global plc have a knowledge management system that helps the organization create and maintain a strong knowledge management system to achieve sustainable growth. Besides this, the Paper can demonstrate that knowledge management is a crucial driver of organizational performance