Assesment Of Conorrhoea And Syphilis In Patients Attending Clinics For Sexually Transmitted Diseases In Addis Ababa

In this study a total of 754 individuals were involved. Thernstudy population was divided into 3 ~roups: a/200 (27%) pre~nantrnwomen, b/l05 (14%) students, and c/449 (59%) patients attendingrnclinics for STDs. Blood samples collected from all members ofrnthe study population, were examined for syphilitic infection. Arnseroprevalence of 13%, 11.2% and 21.6% were found among pregnantrn"homen, students and STD patients by both RPR and TPHArnrespectively. The validity of RPR as a screening test wasrndetermined using sensitivity, specificity, percentage of positivernpredictive value and efficiency. Strong positives and positivesrnby the RPR test can be considered as positive for syphilis. Onlyrnweak positives require retesting. Endocervical and urethralrn(male) discharge samples, collected from 233 STD patients inrnaddition to the blood samples, were examined for the presence ofrnNeisseria I{onorrhoeae. The organism was isolated from 68 (29.2%)rnsub.i ects. Among the isolates, PPNC strains comprised 48 (70%) ofrnthe samples. PPNC strains Were resistant to penicillin (100%),rnampicillin (96%). bactrim (91%) and kanamycin (22%). Of the nonPPNGrnstrains 25% were resistant to pencillin. 20% to ampicillin,rn40% to bactrim and 15% to kanmycin. Both groups were, however.rnsensitive to erythromycin, tetracycline, chloramphenicol andrnceftriaxone.

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