Serum Immunoglobulin Levels In Healthy Ethiopian School Children

Serum conc ent r ations of immunoglobulins 19G, 19A and 19M inrn258 healthy Et hiopian school children and 82 healthy adults residingrnin Addis Abeba were measured by the r adial immunodi ffusionrnt ec hnique . The r esults a r e presented as geometric mean valuesrnin mg/100 ml and as percent of the adult mean val ues. A statis- •rntical analysis showed that the 19G a nd 19A concent r a tions atrnages 8 and 7 r espectively were lower than the adult values . Therninfe renc e drawn from these r esults is that the 19G and 19A l evelsrndo not r each the adult l e vel until a fter the age of 8 and 7rnr espective l y . In c ontras t the 19M l evel was found to reach t hernadult l e v e l before the age of 7 . No truly significant differencesrnwe r e observed in immunoglobulin l evels which could be attributedrnto se x , intestinal pa rasitic infection or socio-economic status .rnThe mean values for IgG and 19M obtained from this study werernfound to be higher than the r e ferenc e values being used in therncountry a t the mome nt. I t is thus suggested that mean immunoglobulinrnconc entration val ues obtained from this s tudy be usedrnas r e f e r ence values until furth e r study is made and more r e finedrnr e f e rence value s ar e set .

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