Background: Cervical cancer is preventable and remains a leading cause of avoidable deathrnamong women in the world. In developing country, the knowledge of screening for cervical cancerrnbehavior still very low, the converge of cervical cancer screening was from 2.0% to 20.2% in urbanrnareas and from 0.4% to 14.0% in rural areas. Previous findings of research were indicated that thernmagnitude of screening for cervical cancer in Ethiopia is very low, which is about 0.6%, thisrnindicated the knowledge of women is low because, of the women did not come to screened forrncervical cancer. rnMaterials and Methods: A cross-sectional study design was used. Data were collected using arnstructured self-administered questionnaire. Analysis was conducted using SPSS version 23. rnResults: About 312 urban health extension workers were included in this study. The mean age (Â±)rnstandard deviation) of the study participant was 20.41 years Â± SD, 3.73 years). Based on thisrnfinding, about 48.4% of the participants have good level of knowledge about cervical cancerrnscreening and about 43.3% of the participant who were source of information were healthrnprofessionals. A multiple logistic regression were performed to identify the existence andrnsignificance of association, work experience and monthly income were significantly associatedrn[AOR = 4.32, 95% CI: (1.71, 10.94], monthly income [AOR = 3.75, 95% CI: (1.49, 9.41) andrn(A0R= 3.08 95% CI: (1.06, 8.98) were associated. rn rnConclusion: This study has revealed that the knowledge towards cervical cancer screening wasrnpoor among urban health extension workers of Addis Ababa, health centers. Generally,rninformation could be subordinate than seems in this explore. In conclusion, knowledge towardsrncervical cancer screening and when should be screening showed several misunderstandings. Basedrnon this misunderstanding, continuing delivering information to encourage screening includingrnhealth extension workers to raise the knowledge of women.