This study focuses on GIS based mapping of high HIV/AIDS vulnerable areas ofrnAddis Ababa city which helps planning and wise allocation of resources to prevent thernspread of the epidemic. In this study GIS techniques were found to be useful to offerrnhelpful information on the spatial distribution of HIV/AIDS risk factors. Using GIS, differentrncriterion (factor) maps have been prepared; these maps are the Female Population Densityrncriterion map, the Young Population Density criterion map, the Economically Inactive (LowrnIncome) Population Density criterion map, the Commercial Sex-workers Density criterionrnmap, and the Establishments (i.e. those establishments that incorporate the commercialrnsex-workers as part of their business) Density criterion map. A map that shows the existingrnHIV positive population density was also prepared and used to assign weights to therncriteria maps. Different GIS data processing techniques have been deployed to extractrnspecific information for the required analyses. Spatial multicriteria decision analysisrnapproach was used for selecting evaluation criteria and deriving commensuratern(standardized) criteria maps. Criteria weights were derived on the basis of the Pairwiserncomparison method. The GIS analyses indicated that sex-workers concentration is high inrnthe central northwestern part of the city. Similar results were found for the femalernpopulation distribution, the young population distribution, and the distribution ofrnestablishments that incorporate commercial sex-workers as part of their business. Thernresult of the GIS analysis showed that 4% of the total area of the city is found in thern‘Highest Susceptible’ zone. This zone includes in particular Woreda 7, Woreda 6, Woredarn5, and Woreda 4 areas of the city. The result also showed that 11%, 34% and 51% of thernareas of the Addis Ababa city are found in the ‘Higher’, ‘High’ and ‘Low’ susceptible zonesrnrespectively. The spatial distributions of the existing VCT centers and the developedrnHIV/AIDS susceptibility map show some degree of correlation. When it is intended to openrna new VCT center, it is recommended that first priority should be given to those areasrnwhich have sparsely distributed VCT centers; doing so increases the accessibility to VCTrncenters which are the first and most important step to combat the disease.