The HIV/AIDS epidemic has affected millions of people all over the world and the effectrnof the pandemic has been particularly striking in Sub-Saharan Africa. As a Sub-Saharanrncountry Ethiopia has been launching many projects to tackle the spread of HIV/AIDSrnsince 1986 (MOH: 2006).rnTigray is one of the nine federal states of Ethiopia located in the northern most part of therncountry. Studies show that the Ethio-Eritrean war of 1998-2000 resulted in significantrnincrease in HIV prevalence in the region, where the majority of the Ethiopian DefensernForces were stationed (Berhe et al, 2004:1).rnThe military may be described as one of the high-risk groups in HIV/AIDS because of itsrnmobile nature. It may be argued that the region faces an additional AIDS threat becausernof the massive military presence at present. Added to this is the large number of sexrnworkers who are believed to be in the major towns of the region following in thernfootsteps of the defense forces. And it appears that their presence poses an additionalrnthreat to community health in the Region.rnThe project paper tries to assess the extent to which the Voice of the Revolution of Tigrayrn(VORT) which is transmitted in local Tigrigna language has been effective in setting thernissue of HIV/AIDS as an agenda among its audience in Mekelle town and mobilizing thernaudience for participation.rnThe study has employed both quantitative and qualitative methods. These include arnsurvey, observation and quantitative description of content and in-depth interview. Thernresearch was conducted in Mekelle town; using purposive sampling on two of the eightrnTabias (Sub-Urban centers).The researcher distributed 219 copies of questionnaire torngather data. In addition to this, the researcher has carefully studied the letters ofrncomments sent to the station from listeners to examine the degree and level of audiencernparticipation in the HIV/AIDS programs produced by the radio station and also analyzerntheir main concerns.Moreover,the researcher has employed in-depth interviews withrnrepresentatives of different associations, the regional HIV/AIDS Prevention and ControlrnOffice, and journalists to find out what the agenda they were trying to set was .The resultrnof the research shows that the radio station has been able to persuade the audience tornconsider HIV/AIDS as a top priority issue of concern. However, it was learned that thern9rndegree and level of audience participation especially on the HIV/AIDS radio program isrngenerally not encouraging compared to the other programs of the radio station. Of all therntotal respondents the majority reported that they didnâ€™t participate by writing a letter andrnthe researcher didnâ€™t find listeners views and through call-ins and personal visits. Thernlevel of participation of the various segments of the society is too low. And the timernallocated for the HIV/AIDS programs is not enough.rnThe research analysis shows that the radio station has to work hard to meet the needs andrnaspirations of the audience.