Ethiopia has a largest number of podoconiosis patients who are suffering from enormousrnsocioeconomic burden of the disease. Despite this fact, the issue of education of childrenrnand young people living with the disease has given little attention. Stigma andrndiscrimination toward the patients coupled with disease related complications has deniedrnmany patients enjoyment of the right to education. This paper dedicated to assessrnrealization of the right to education of children and young people living withrnpodoconiosis in Wolaita Zone. To this end, cross-sectional qualitative study is employedrnto assess implementation of international and national commitments pertinent to the rightrnto education of children and young people living with podoconiosis. In-depth interview,rnkey informant interview and focus group discussions were employed as data gatheringrntools. The primary source of data were children and young people living withrnpodoconiosis, school directors, parents or guardians of children and young patients,rnconcerned government body and NGOs. A total of 107 participants of the study werernselected using purposive and convenient sampling techniques. Secondary source of datarnare government policy and legal documents, and annual reports regarding educationrnrights.rnFinally, qualitative data collected, interpreted and analyzed. The core findings of thernstudy are; the study finds out that disease related illness and complications are the causernof absenteeism, poor educational performance, repetition and complete drop-out ofrnschool among students with the disease. In disease endemic areas of Wolaita Zone,rnschools are not available, accessible, acceptable and adaptable to school-age children andrnyoung people living with the disease. Apart from this, the study disclosed thatrnmisconception about the disease among the school community, widespread stigma andrndiscrimination against patients; unfavorable school environment and financial constraintsrnare the major barriers to the enjoyment of the right to education by children and youngrnpeople living with podoconiosis. These led to the conclusion that, though there arernfavorable policy and legal environment, it is far from being realized for children andrnyoung people living with podoconiosis.