Among the stool samples of 205 patients tested for bacteriological cultures, only 6 (2.9%)rnwere positive for Yersil/ia, 22 (10.7%) for Salmonella. 12 (5.8%) for Shigella and 11rn(42.3%) for diarrhoeagenic E. coli. Out of the Yersil/ia spp. totally isolated in this study,rnonly 3 (1.5%) were Yersil/ia enterocolitica and 3 (1.5%) were Yersil/ia pestis. AmongrnYersil/ia el/terocolitica strains two were isolated from children while one was from adultrndiarrhoeal patients. Similarly, 2 of these strains were from male patients, while 1 was fromrnfemale patients. With regard to Yersinia pestis all strains were isolated from males, ofrnwhich 2 were from children and one from adult diarrhoeal patient. The standardized agar disk-diffusion technique was used with disks of 13antmicrobialrnagents (ampicillin, carbenicillin, cephalothins, chloramphenicol, gentamycin, kanamycin,rnnalidixic acid, norfloxacin, polymyxin B, streptomycin, sulphadiazene, tetracycline, andrntrimethoprim-sulphamethoxazole. All (51) strains of enteric pathogenic bacterial isolatesrnwere sensitive to nalidixic acid, norfloxacin, and polymyxin Band 46 strains were resistantrnto cephalothin. Sensitivity to gentamycin, nalidixic acid, norfloxacin and polymyxin B isrngreater than 90% of the tested strains, while resistance to cephalothin, ampicillin and.rntetracycline was greater than 50%. All strains of Yersil/ia ellterocolitica and Yersinia pestis were sensitive to carbenicillin,rnchloramphenicol, gentamycin, kanamycin, nalidixic acid, norfloxacin, polymyxin B,rnstreptomycin, sulphadiazene and trimethoprim-sulphamethoxazole. All strains of Yersiniarnenterocolitica were resistant to ampicillin. Among Yersinia pestis strains, 66.7% werernresistant to ampicillin and cephalothin respectively while 33.3% of the strains werernresistant to tetracycline. Out of 22 Salmonella strains, all isolates were sensitive to norfloxacin, polymyxin B andrnnalidixic acid while 21 (95.5%) of strains were sensitive to gentamycin and kanamycin.rnResistance was found 86.4% against cephalothin, 36.4% ampicillin and 27.0%rnsulphadiazene and both streptomycin and trimethoprim-sulphamethoxazole in 22.7% of these strains. Eleven different combinations of resistant patterns were observed for all thernSalmonella strains.rnAll of the 12 strains of Shigella were sensitve to nadixic acid, norfloxacin, polymyxin B,rngentamycin and kanamycin. Ampicillin, carbenicillin, cephalothin, streptomycin,rnsulphadiazene, tetracycline and trimethoprim-sulphamethoxazole were sensitive against ::;rn50% of Shigella isolates. Among the isolates, 91.7% were resistant against tetracycline,rn50% against cephlothin, 75% against each of ampicillin and strepomycin. Totally, 10rndifferent patterns of resistance were noted for Shigella spp.rnAll strains of diarrhoeagenic E. coli were sensitive to gentamycin, kanamycin, nalidixicrnacid, norfloxacin and polymyxin B. While 90.9% of. them were sensitive tornchloramphenicol. Of all these isolates, 81.8% strains were resistant against cephalothin andrn63.6% against sulphadiazene.rnBased on the above sumrnerized results the prevalnece and antimicrobial response ofrnYersinia spp. is discussed in comparison with those of Salmonella, Shigella and E. colirnisolates. According to this study, gentamycin, kanamycin, nalidixic acid, norfloxacin andrnpolymyxin B were effective to treat diarrhoeal patients against enteropathogens.