This study examined the psychosocial challenges particularly that ofrndepression, anxiety, stress, fear, stigma and discrimination of peoplernliving with HIV/AIDS, N=200 (lOOmale, 100female), and the copingrnstrategies they employed. Data were collected by means of structuredrninterview schedule. Case study and focus group discussion were used torngather inÂ·depth individual data. Depression, anxiety and stress werernassessed by using Center for Epidemiologic Studies Depression Scalern(CES'D), Beck Anxiety Inventory (BAI) and Perceived Stress Scale-10 (PSS-rn10) respectively and others by a set of items developed by the researcher.rnResults revealed that 56 % of the participants experienced clinicallyrnsignificant symptoms of depression with mean score of 2.60 and 40 % ofrnthe respondents showed clinically significant anxiety symptoms withrnmean score of 32.31.The mean score of perceived stress was 24.52rn(S.D=5.64) where 50.50 % of the respondents scored above the mean. Thernmean score of stigma and discrimination using Likert type scale wasrn32.94 (S.D=11.34) where 58.4 % of the respondents scored above thernmean. The participants of the case study also showed episodes ofrndepression, anxiety, stress, fear, stigma and discrimination.rnStatistically s ig nificant differences were found between males' andrnfemales ' scores of depression and stigma and discrimination at 0.05rnlevel with 95% confidence interval and 191 and 194 degrees of freedomrnrespective ly. Females participants were found to experience morerndepression and stigma and discrimination than male participanÂ·t s . Nornstatistically significant differences were found between males' andrnfemales' scores of anxiety and stress.rnThe most often utilized coping strategies identified by the participantsrnwere: listening to music, Praying to God, try on their own to deal with thernproblem, day dreaming and talk to a friend. The participants alsornreported low utilization of certain maladaptive coping strategies such asrnalcohol and chewing 'chat'.