According to WHO Global report, in low-income countries more than half of deaths attributable to poor glycemicrncontrol are premature. Studies compassed, prevalence of poor self-care practice and glycemic control is by nowrnin tip of iceberg above diabetes by becoming primary offender for fired morbidity and mortality but; are neglectedrntragedy. Currently diabetes patients are exposed to intolerable cost of dialysis and organ transplantation becausernof poor glycemic control and self-care practice induced complications; which in turn increased beggar populationrnand prevalence of suicidal attempt. Studies underlined, optimum self-care practice is needed to avert theserncomplications via adjusting glycemic control status. However, only a minute of relevant studies were conductedrnin Ethiopia to assess this problem.The aim of this study was to assess glycemic control and self-care practicernamong diabetes patient in Dawro Tercha General Hospital. Cross-sectional study was conducted from March 07Aprilrnrn10/2020 in Tercha general hospital among 220 participants selected by systematic sampling technique.rnLogistic regression analysis was carried out to identify independent predictors. rnStatus of self-care practice and glycemic control became good for 24.9% and 23% respectively. Age, diabetes rncomplication, medication adherence, glucometer and appointment adherence were nominated in shortlist ofrnindependent predictor for glycemic control; whereas education, diabetes complication, diabetes category, distancernand appointment adherence became independent predictors for overall self-care practice. Furthermore, presencernof significant association between glycemic control and self-care practice was assured. Status of good glycemicrncontrol and self-care practice were shine red lump, since it indicates majorities of the patients were closed to facernpremature death and permanent disabilities. Association between glycemic control and self-care practice on thernother hand uncovered presence of non-pharmacological intervention under question, and further brightened thernneed of maximum effort to enhance self-care practice to ease roads to good glycemic control and finally to saverndiabetes patients from the coming fatal consequences.Responsible bodies have to work hard to raise the coverage ofrnhospital or to enhance material capacity of available primary hospitals to enable them to serve diabetes follow uprnpatients, since all patients in the whole zone in this study area served by only one hospital. Health education team has tornbe formed to provide problem solving-centered education supported by Audio visual aids.