Introduction: Nurse‟s job sat isfact ion is a cornerstone for improving the qualit y of health care, rnpatient satisfaction, staff morale, job competence, patient compliance, positive patient outcomes rnand its continuity of care; however, dissatisfaction leads to decreased productivity, efficiency, rnand the quality of care, each of which raises costs to the health care system. rnObjective: The main objective of this survey was to assess levels and determinants of nurses‟ job rnsatisfact ion by using Herzberg‟s job motivator and hygiene factors in Addis Ababa government rnhospitals. rnMethods: Institution based cross-sectional study was conducted from Nov to May 2010 on 300 rnnurses working in Addis Ababa government hospitals. Pre-tested and self administered rnquestionnaire was used to collect data from six hospitals. Simple random and systematic rnsampling technique was employed in this study. The data was entered, cleaned and analyzed rnusing SPSS version 15. Associations between dependent and independent variables assessed and rnpresented using frequency, mean, standard deviation, student t-test, ANOVA, & Pearson‟s rncorrelation test. Statistical significance was set at p-value < 0.05. rnResults: Three hundred nurses responded from the sampled 314 respondents and composed a rnresponse rate of 95.5%.The majority 188 (63%) of nurses were dissatisfied with their job. rnAdvanced age and work experience were related with nurses‟ job sat isfact ion. The overall mean rnsatisfaction score of hygiene and motivation factors were 3.54 (+0.96SD) and 3.35 (+0.09SD) rnrespectively. Almost all determinants were positively and moderately correlated with job rnsatisfaction, whereas compensation was negatively and strongly correlated with job satisfaction. rnConclusions: The majority of nurses were dissatisfied with their job. Advanced age and work rnexperience were statist ically significant and associated with nurses‟ job sat isfaction. Almost all rnhygiene and motivation factors were positively and moderately correlated with nurses‟ job rnsatisfaction. Hygiene factors were more important predictors of job satisfaction than motivation rnfactors in this study subjects. The study subjects were not satisfied with the compensation rn(salary) that they received for their work that they do. rnRecommendations: Managers can use both hygienic & motivation determinants as a strategic rntool to increase nurses‟ job sat isfact ion and they should also give priorit y and design appropriate rnmechanism to their young and low experienced nurses to improve level of their job satisfaction. rnThe factors contributing to nurses‟ dissat isfact ion with compensation (salary) should be further rninvestigated and depending on the findings, alternative methods of reward need to be considered.