Survival Status And Predictors Of Mortality Among Adults With Covid -19 Attending Eka Kotebe General Hospital Addis Ababa Ethiopia 2021

Coronavirus disease (COVID-19) affect peoples throughout the globe and is becoming a seriousrnthreat to the health and wellbeing of people. The disease has a higher transmission rate and arngreater risk of morbidity and mortality. This study aimed to assess survival status and predictorsrnof mortality among adults with COVID -19 attending Eka Kotebe General Hospital, AddisrnAbaba, Ethiopia, 2021. A retrospective follow-up study was conducted among 602 Adults withrnCOVID-19 attending Eka Kotebe General Hospital from March 13, 2020, to November 13,rn2020. Patient charts were selected using a simple random sampling method. The data werernentered by Epi- data version 4.2 while analysis was carried out using STATA version-16. ArnKaplan Meier survivor curve was computed to estimate the survival probabilities. A Long-rankrntest was used to compare the difference in survival curves between categories of covariates. Coxrnproportional hazard models were fitted to identify predictors. Hazard ratio with a 95%rnconfidence interval was computed to determine the level of significant association. Onrnmultivariable analysis, those variables having a p-value of ≤0.05 were considered staticallyrnsignificant. In this study, out of 602 participants, a total of 514 Adults with COVID-19 wererncensored and 87 have died with an incidence rate of 10.7 per 1000 person-day observationsrn(95%CI: 8.79, 13.38). The median survival time of adult COVID-19 patients was 21 days. Olderrnadults(≥65year) (AHR:2.22,95%CI:1.02,4.86), being Men (AHR:3.04,95%CI:1.61, 5.74),rnshortness of breathing at admission (AHR:2.29,95%CI:1.16,4.54),comorbidity (AHR: 2.23,rn95%CI:1.04, 4.80),Diabetes Mellitus (AHR 2.31,95%CI:1.30,4.08),cardiac disease (AHR: 2.07,rn95%CI: 1.21, 3.43) and baseline White blood cell count of greater than 10 (103/µL) (AHR 2.62,rn95%CI: 1.55, 4.44) were identified as independent predictors of COVID-19 mortality. A majorrnpredictor of time to death of COVID -19 patients were found to be male sex, older adult (≥65rnyears), having shortness of breathing at admission, having at least one comorbidity, diabetesrnMellitus, Cardiac disease, and baseline White blood cell count of greater than 10(103/µL).rnTherefore, concerned stakeholders should focus on the above-mentioned predictors of mortalityrnand design interventions accordingly to enhance the survival of COVID-19 patients.

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