A cross sectional study on smallholder dairy production technologies uptake in mixed farming systems in Dejen â€œworedaâ€ was conducted from September 2007 to May 2008 with the objectives to identify available technologies, their uptake levels and constraints, assess the influences of these technologies on milk production and reproductive performance of dairy cattle in the study area. Totally, 240 randomly selected smallholder farmers and six participatory appraisal discussion groups were included in the study. Information was collected by questionnaire survey, personal observation during farm visits and through participatory appraisal group discussions. The average family size in the study area was 5.38 + 1.96 ranging from 1 to 11 persons while the average land holding and livestock size were 1.41+ 0.68 and 5.01 TLU respectively. Cattle represented the largest proportion [49.5 % (4.14 TLU)] of the livestock population. Cows were 30.3% of cattle herd and 20% of them were crossbred. The average daily milk yield was 1.46+ 0.99 and 6.01+ 3.20 liters for local and crossbred cows respectively. Totally, 25 dairy technologies practiced by smallholder farmers were identified in the study area. Technologies that were widely used (more than 80% uptake levels) were modern endo-parasite treatment, vaccination, estrous detection and haymaking. Technologies such as pregnancy test, modern ecto-parasite treatment, total and partial stall feeding, crossbreed cattle, forage development, feed supplement, artificial insemination (AI), separate type of house, bull station, udder washing and record keeping were at intermediate uptake level. Modern milk processing, urea treated straw (UTS) and silage were the least practiced technologies with an uptake level of 1.7 to 14%. Associations of technologies uptake with different farm household characteristics of smallholders were tested by using one way ANOVA. Male headed households adopted significantly (P