Comparison Of Perioperative Blood Glucose Concentration In Spinal Versus General Anesthesia In Patients Undergoing Elective Lower Abdominal And Pelvic Surgery At Tikur Anbessa Specialized Hospital Addis Ababa Ethiopia202021a

Introduction: Surgery is linked with fear and stress that disrupt metabolic and neuroendocrinernactivities which impair normal maintained glucose metabolism that leads in stress hyperglycemia.rnAnesthesia inhibits the stress responses and hyperglycemia but the mechanism at which theyrnreduce surgical induced hyperglycemia is different. rnObjective: This study compares the effect of GA and SA on perioperative blood glucose levels inrnpatients that undergo lower abdominal and pelvic surgery at Tikur Anbessa Specialized Hospital. rnMethod: An institutional-based prospective cohort study was done on 70 individual patients; 35rnin each group that undergo lower abdominal and pelvic surgery under GA and SA by using arnsystematic random sampling technique. Capillary blood glucose was measured 4 times: T1; 5rnminutes before induction in GA and giving SA, T2; after 5 minutes of induction in GA andrncomplete block in SA, T3; immediately at the end of surgery in both groups and T4; 60 minutesrnafter the end of the surgery in both groups. Collected data were entered into SPSS version 24 andrnthe normality was checked by the Shapiro Wilk test. For statistical analysis unpaired t-test andrnpaired t-test were used to compare the mean of normally distributed data between the two groupsrnand within the group respectively, presented by mean and standard deviation. Manny Whitney Urntest was used for asymmetric data and presented by median and interquartile range. Categoricalrndata were presented by percentage and analyzed by chi-square test. P values

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