ABSTRACT rnBACKGROUND: The knowledge of the pattern of admission and treatment outcome of criticallyrndiseased pediatric patients admitted to pediatric intensive care units in developing countries wherernthe resource is scarce may help for the identification of priorities and resources to make the facilityrnbetter. The prevalence of pediatric intensive care unit mortality often varies globally, dependingrnon the facilities of the intensive care unit, the availability of workers, and admission patterns. rnOBJECTIVE: The objective of this study was to assess admission pattern and treatment outcomernof children admitted to a pediatric intensive care unit (PICU), at Tikur Anbessa specializedrnhospital, Addis Ababa Ethiopia, from October 2018 to October 2020 rnMETHODS: The study was a cross-sectional study design among 361 pediatrics patients admitted rnto the pediatric intensive care unit of Tikur Anbessa Specialized Hospital Addis Ababa Ethiopiarnfrom October 2018-October 2020 by using a systematic random sampling technique. Descriptivernstatistics were summarized with data, tables, and figures for display results. The distribution of therndata was checked with a normality curve. Bivariate and multivariate analyses were used to see thernassociation of an independent variable on the outcome variable. Factors with a p-value of less thanrn0.2 in bivariate analysis were exported to multivariate analysis to see if they are independentrnfactors for the outcome variable. The adjusted odds ratio was used to show the strength ofrnassociation with a 95% confidence interval and the p-value of less than 0.05 was taken as statisticalrnsignificance in multivariate analysis. rnRESULTS: A total of 361(100%) charts were sampled for data collection; 197 (54.6%) were malernand 164(45.4) were female. The most common cause of admission was, septic shock (27.14%),rnwhereas the least cause of admission was Asthma 9(2.50%). The mean age at admission wasrn39.44Â±44.87 months. The overall mortality rate of our pediatric intensive care unit was 43.8%.rnFrom multivariate regression analysis need for mechanical ventilation (AOR= 11.08, 4.25-28.87,rn95%CI, P=0.001), need for inotropic (AOR = 10.67, 4.09-27.81,rnrn95%CI P