Background: Transverses abdominals plane block was a kind of nerve block performed on the trianglernof petit to block a number of abdominal nerves.rnObjectives: To assess analgesic efficacy of transversusabdominis plane block after cesareanrnsection delivery under spinal anesthesia at zewditu memorial hospital from February to marchrn2016.rnMethods: A prospective cohort study design was conducted. 42 patients undergoing caesareanrnsection under spinal anesthesia were followed postoperatively. Those who undergo TAP blockrnwith bupivacaine (n = 21) versus non-TAP (n = 21) with standard analgesia with intravenousrnagents were followed. Each patient was assessed post-operatively by a blinded investigator forrnvisual analogue score (VAS) at 2, 4, 6 and 12 hours, time to 1st analgesic request and totalrnanalgesic consumption with in the 1st 12 postoperative hours. SPSS window version 20.0rnsoftware was used for analysis.rnResults: Postoperative VAS outcomes based on( mean Â±SD) for TAP group and non- TAP grouprninclude at 2 hr (5.23Â±3.34) vs (15.28Â±6.51), at 4 hr (7.09Â±3.11) vs (17.52 Â± 3.9) , at 6 hrrn(8.9Â±4.63) vs 21.04Â±5.06) and at 12 hr (11.33 Â± 4.98) vs (25.2 Â± 5.9).There was also decreasedrnpostoperative analgesic consumption and increased time to 1st analgesia in TAP group.rnConclusion and Recommendation: It is concluded that bilateral single injection of TAP blockrnprolonged the time to 1st analgesic request , reduced total postoperative analgesic consumptionrnand had lower postoperative severity of pain when compared with non TAP groups in patientsrnafter cesarean section under spinal anesthesia when it is used as part of multimodal analgesia. Irnrecommend TAP block as part of multimodal analgesia after cesarean delivery. I also recommendrnfurther study to find out the effect of TAP block after 12 hr