Attempts Towards The Synthesis Of Substituted Pyrrolines

In this project, the reactions of several functionalizedrncompounds possessing the nicotine skeleton have beenrninvestigated. Studies also have been conducted onrnthe cycloaddition reactions of C-pyridyl-h-methylnitronernwith three olefinic compounds namely, allyl chloride,rnallyl bromide and allyl alcohol. Plausible mechanismsrnhave been suggested for the formation of nicotine and nicotyrinernby the reduction of 5-methoxycotinine and relatedrncompounds with lithium aluminum hydride.rnIn the course of this work four new compounds, namelprn4-hydroxynicotine, 4-chloronicotine, 4-hydro:

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