Phytochemical Investigation On The Ethanol Extract Of The Aerial Parts Of Laggera Tomentosa

Laggera tomentosa in the family of Asteraceae, is a species endemic to Ethiopia.rnIt has medicinal values and is important in the traditional medicine like the otherrnspecies in the genus. In this project work, one sesquiterpene and one flavone,rnnamely 3-(3’-acetoxy-2’-hydroxy-2’-methylbutyryl)cuauhtemone (LTE-1) and 4’,rn5,7-trihydroxy-3’,3,6-trimethoxyflavone (LTE-2) were isolated from the aerial partsrnof the plant, respectively. LTE-1 was isolated before from the same plant andrnother species of Laggera. LTE-2 was reported before from Jasona montana plantrngrowing in Egypt and Mentha royleana with the name Jaceidin. However, it wasrnisolated for the first time from L. tomentosa. The structures were elucidatedrnbased on NMR and UV spectra and by comparison of the data obtained withrnthose reported for related compounds in the literature

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