The study of status and trends of fish and fisheries in Lake Langeno (also known in the literaturernas Langano), Ethiopia was conducted from March 2014 to February 2016. The basis for this studyrnwas that fish stocks were subjected to uncontrolled fishing over many years and available data onrnthe status and trends of fishes in the lake has become unreliable for management and sustainabilityrnof the sector. In order to examine the diversity, habitat preference and seasonal distribution, spatialrnand seasonal data were collected from six different sampling sites by using gillnets of variousrnmesh sizes and long lines. Data were analyzed by Canonical Correspondence Analysis (CCA),rnSPSS software and by various descriptive statistics. The results indicate physico-chemicalrnparameters showed no significant spatial variation, but high seasonal variation. A total of sevenrnfish species dominated by family Cyprinidae were identified (Hâ€™=1.264). Carassius carassius, wasrnnot reported in previous studies, now comprise 0.64% of the total collected specimens. All the fishrnspecies were collected from all of the sampling sites, except at one site (Middle), where Carrasiusrncarassius and Garra dembecha were absent. Index of relative importance (IRI) was essentiallyrnsimilar for all the sampling sites, but differed in the relative importance of each species with thernhigh importance of Oreochromis niloticus. Principal Component Analysis (PCA) did not producerndistinct habitat-associated species patterns across the sampling sites. However, temperature andrndepth seemed to be the key environmental factors determining fish community structure in thernlake. The results showed that the composition of the fishes has undergone some changes duringrndata collection from what was reported in the literature. The Length-weight relationships of O.rnniloticus, E. paludinosus, C. gariepinus, L. intermedius and C. carpio were curvilinear (b=2.872,rn2.554, 2.823, 2.771 and 2.919, respectively), and statistically significant (p>0.05) except forrnEnteromius paludinosus. For both sexes, the mean Fulton Condition Factor values of Oreochromisrnniloticus, B. paludinosus, Clarias gariepinus, Labeobarbus intermedius and C. carpio werern1.77 }0.37, 1.06 }0.44, 0.60 }0.5, 1.33 }0.44 and 1.47 }0.83, respectively. A better body conditionrnwas recorded in the dry seasons for all species except for O. niloticus. All fish species hadrnrelatively smaller maximum size and poor body condition than what was reported for fishes inrnmost of the Ethiopian water bodies. Females were more abundant than males for all fish species,rnand the sex ratio of O. niloticus (1.13:1)and E. paludinosus (1:.24:1) was significantly differentrnfrom the hypothetical distribution of 1:1 (Ï‡2, p