Electrochemical Determination Of Folic Acid At Polybromocresol Purple Modifed Glassy Carbon Elelctrode

Polybromocresolpurple (PBCP) was used for the modification of glassy carbon electrodern(GCE) to determine the electrochemical behavior of folic acid (FA) in 0.1 M PBS at pH 7.0rnat the scan rate of 100 mV/s. The modified electrode was characterized and used tornelectrochemically determine FA using cyclic and differential pulse voltammetry. Thernoxidation peak current of FA at the modified electrode increased compared to the barernGCE, hence indicating that the BCP displays a significant improvement on thernelectrochemical oxidation of FA. The oxidation peak current of FA is proportional to itsrnconcentrations in the range of 20-100 μM with 0.987 correlation coefficient. The detectionrnlimit was found to be 1.772 μM. Based on the relationship between the oxidation peakrncurrent and square root of scan rate, the overall electrode process was found to be diffusionrncontrolled at BCP/GCE. The modified electrode exhibited good sensitivity, andrnreproducibility for the determination of FA, indicating the capable applications of thernmodified electrode in real sample analysis.

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