Occupational diseases are hard to track for many reasons and usually were underreported. It is because they do not have unique pathologies and their long latency period. The automotive refinishing industry is a common setting of occupational exposure to isocyanates.rnThe goal of this study was to examine the prevalence of chronic respiratory symptoms in automobile spray painting workers due to long term exposure to aerosols in the working environment and to compare these results with changes in spirometric parameters. And also the study aims to assess the knowledge, attitude, and practice (KAP) of the workers to automobile spray painting related respiratory diseases.rnA modified questionnaire on respiratory symptoms from the British Medical Research Council was used to take the data about respiratory symptoms. Spirometric parameters were determined using a Mijnhardt spirometre, Vicatest-P1. Aerosol measurements was done using MIE DataRAM 4 (for data-logging Real-time Aerosol Monitor 4), model DR-4000 which is a technologically advanced instrument (embodies U.S. patent No. 6,055,052) designed to measure the concentration of airborne particulate matter (liquid or solid), as well as mean particle size, air temperature and humidity, providing direct and continuous readout as well as electronic recording of the information.rnThe study included 41 automobile painting workers from eight auto body workshops in Addis Ababa, Ethiopia. All subjects were men, but they differed in age and years of service. The group used for comparison consisted of 30 male office workers in Addis Ababa who had never been exposed to this kind of air pollution before. All the subjects were non-smokers.rnAutomobile painters mostly complained of cough and wheezing associated with the workplace (29.3%, 53.7%) and also phlegm and breathlessness (24.4%, 21.9%) respectively. This indicated that the prevalence of chronic respiratory symptoms reported by the examined automobile spray painters was quite high. Results of lung function measurements were recorded on a decade age group. Comparing the lung function measurement results for FVC and FEV1 across all age categories of the study subjects,rnxiirnxiiirncontrols have greater lung function measurement results which also indicated statistically significant difference ( p-value