Wet coffee processing wastes and human urine (HU) are among the high volume and nutrient-rich wastes that can be reused to increase productivity. This thesis reports the optimum combination ratios, soil fertilizing potential, and post-harvest effects of coffee processing wastewater (CPWW) and hydrolyzed HU in using as a liquid fertilizer, and as additive for coffee pulp (CP) composting. In-vessel composting experiment was conducted in five treatments: C0 (CP, control), C1 (CP + CPWW), C2 (CP + 1:1 CPWW: HU), C3 (CP + 1:2 CPWW:HU) and C4 (CP + 1:3 CPWW:HU). Besides, nine triplicate treatments of HU-CPWW were prepared as T0 (rainwater, -control), T1 (CPWW), T2 (1:1), T3 (1:2), T4 (1:3), T5 (2:1), T6 (3:1), T7 (HU only) and T8 (a mineral fertilizer (MF), + control). Each of the treatments were applied for pot based cabbage cultivation using a completely randomized design (CRD) in a greenhouse with triplicates. Moreover, the optimum treatments from each of the organic fertilizers were applied in field using completely randomized block design (CRBD). The composting data showed that supplementing HU-CPWW optimized conditions for CP degradation and upheld the humification process manifested by a significant organic matter (OM) reduction, and NO3--N (12.85-78.14%), P (35.38-47.98%), and K+ (> 27.57%) increment. The NH4+-N percent reduction, its concentration, and the NH4+-N:NO3--N after composting were 62.16-82.66%, 90% germination index (lowest phytotoxicity) was obtained in C2 and C3, respectively. Cabbage yield of T3 was comparable to that of compost (C3) and MF in the pot experiment, but significantly lower in the field (F=77.87, p=0.001). Generally, T3 and C3 had the optimum growth and yield parameters which can substitute the effect of MF for cabbage cultivation. The soil organic carbon and available phosphorus after production in T3 and C3 were significantly increased. The exchangeable sodium percentage, saturated electrical conductivity, and pH values indicated no effects of sodicity, saline-sodicity, and salinity for single round application. The total phenol, tannins, caffeine, Cd, and Cr content of soil was significantly altered with CP compost or HU-CPWW application which also had a significant impact on its content on cabbage, but remained far below the recommended limit. The bio-concentration factor, hazard quotient, hazard index and cancer risk values indicated very little health risk of ingesting the cabbage. However, the effect for repeated applications should be studied, and future studies should also concentrate on minimizing the salinity of the substrate further for sustainable utilization.