It is an orthodox idea that teff has highest content of iron among the majority of cereal-basedrndiet, which provides almost the entire staple food consumed in Ethiopia. However, now a day itrnis proven that it is due to soil contamination. Thus, these leads to two distinctive ideas on therncontaminant iron bioavailability. The current study was, then, initiated with the objective ofrnevaluating effect of different soil contamination on rat of hemoglobin regeneration efficiency.rnThe invivo iron bioavailability of the uncontaminated teff, vertisol contaminated teff, andrncambisol contaminated teff were analyzed and compared against the standard ferrous sulfaterngroup. There was no significant deference in total food and iron intake, weight gain, feedrnefficiency ratio, initial and final hemoglobin, hemoglobin gain, hemoglobin regenerationrnefficiency between and among treatment and control groups (P