Adoptive Transferor Lymphocytes And Its Role In Protecton Against Schist Soma Manzoni Infection In Arvcicanthus Sp Rats

adoptive transfer of protection from inducted donorrnacanthus !!l? rats to uninstructed recipients was attemptedrnby va~yj.ng some parameters such as the inf8ction period ofrndonor rats and the time of transfer relative to challenge.rnConcurrent investigation on the effect of.': 11ctorologousrninfection and fractionation of cells "idS also carried out.rnIt ",as found that cells from 2 month .. ;.nf8ctcd donors hadrnhigh ability to transfer resistance to recipient rats )rnwhile cells f"om 1. 75 and 3 month-infected donors shO.,edrnpartial abi Ii ty and those from 2.5 mont11",infected donorsrnsho"led an unexpected inhibitory effect on transferrnrecipients. Transfers done close to challengu day conferrnalmost complete immunity to recipient rCl"ts, ,:,.~, ..rn'"rnHeterologous cestode infection in these rc:ts appear tornplaya secondary role in protecting against Eo !~ansonirninfections, ,.,hile it ",as also found that unfrilctionated cellsrnhave more ability to transfer resistance thul1 fractionatedrncells.rnPossible immunological mechanisms involvGd during thesernevents ~nd the practical significance of the work arernbriefly discussed.

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