Road Transportation is the fastest growing major contributor to global climate change, accountingrnfor a significant share of worldwide energy-related carbon dioxide CO2 emissions. It is therefore,rnthis sector needs to undertake responsibilities for its environmental impact. This paper introducesrna 3D Eco -Routing Model to reduce environmental footprints of road transports in Addis Ababarncity for distribution vehicles, which adds one more degree of freedom to the system and allowsrndriving routes to be optimized for minimum fuel consumption. The applied model in this studyrntakes into account the effects of road inclination, varying velocity, and vehicle weight to evaluaternthe effects of road inclination on a vehicles fuel consumption and its proportional CO2 - Emissions,rnthe 3D -Routing-Model is applied in three different scenarios within different vehicle weight rangernin the city of Addis Ababa, political capital of Africa, The obtained results indicate that eco-routesrncan yield significant fuel and CO2 Reduction potentials of up to 39.818% in the tested scenariosrnin addition from other pollutants eco routes saves emissions up to 25.650% in the tested scenarios.rnThese numbers designate the importance of considering the topographic characteristics and fuelrnconsumption in routing applications to reduce vehicles emission impacts on the environment.rnThese findings have implications for future investment and policy decisions to concern eco routingrnstrategies.