The experiments on susceptibility of the rice weevil, Sitophilus oryzae (coleoptera: rncurculionidae) to native entomopathogenic fungal isolates were conducted at Addis AbabarnUniversity Insect Science Research Laboratory. The initial cultures of Sitophilus oryzae werernobtained from Holeta Agricultural Research centre. Five different local fungal isolates werernused in the study. The isolates obtained from Addis Ababa University Insect Science Researchrnlaboratory and Desert Locust Control Organization for East Africa (DLCO-EA) AddisrnAbaba. The target concentrations of 1x104, 1x105, 1x106, 1x107, and 1x108 conidia ml-1 werernadjusted for liquid formulations. All experiments were replicated three times. The fungalrnisolates were evaluated by direct spraying of spore suspensions over the target insects. Allrnfungal isolates used in the present study were able to infect and cause death in adults ofrnSitophilus oryzae at all concentrations ranging from 1x104 to 1x108 conidia ml-1.The presentrnstudy showed that Sitophilus oryzae treated with 1x108 conidia ml-1, AAU D is observed to bernvirulent with the least LT50 value 3.52 days and 96.6% mortality in day 10, DLCO 131 killedrn83.33% of the target insect in day 10 with LT50 value 4.45 days, DLCO 141 with LT50 valuern5.32 days and 76.67%mortality , DLCO 26 with LT50 value 6.53 days and 70.00% mortalityrn7 and DLCO 91 with LT50 value 6.21 days and 60.00 % mortality in day 10. The presentrnstudy suggests that biological control of Sitophilus oryzae with local entomopathoges makernin Ethiopia. rnrnKey words: Sitophilus oryza;, Entomopathogen; pathogenecit;, Metarhizium ; Beauveria