Back ground: Pelvic organ prolapse is a health concern affecting millions of women worldwide.rnIt can severely affect a womanâ€™s quality of life by limiting physical, social, psychological andrnsexual function. Significant numbers of women in Ethiopia are also suffering from such problem,rneven at the young age. Vaginal hysterectomy with pelvic floor repair is one of the frequentlyrnperformed surgeries in treating women who have completed their family and are not particularrnabout preserving menstrual function. It is a routine practice to send all these hysterectomyrnspecimens for further histopathologic analysis, to look for the presence of incidental pathologicrnfindings. But routine pathologic examination is inappropriately time consuming, costly, andrncontributes little if anything to the further management of the patient. This study aims to reviewrnthe histologic results of vaginal hysterectomy specimens done for POP.rnObjectives: The aim of this study was to review the histologic results of vaginal hysterectomyrnspecimens done for pelvic organ prolapse.rnMethods: A facility based cross sectional study was done to review the histologic results ofrnvaginal hysterectomy specimens that are done only for uterovaginal prolapse. The study wasrnconducted in Tikur Anbesa Specilized Hospital, Department of Pathology. Four years (Sept 2009rn- Sept 2013) computer saved data and patients medical records were used to analyze the result.rnThe data was entered, cleaned, and analyzed using SPSS 17.0 statistical software.rnResults: Out of the 306 vaginal hysterectomy specimens, histologic analysis was done to all ofrnthe cervical tissues (100%). But histological analysis done only to 4 (1.3%) and 7 (1.9%) of thernmyometrial and the endometrial tissues respectively, because, according to the protocol of thernDepartment of Pathology, tissues other than the cervix will undergo histologic analysis only ifrnthey are found to be abnormal on gross examination. Out of the 306 specimens, only 10(3.2%)rnshow abnormalities on gross examination. On histologic examination, including the cervix,rn40(13.1%) of the specimens had pathologic findings of which only 4(1.3%) were clinicallyrnsignificant, all of which were precancerous cervical lesions, the rest were benign lesions.rnConclusion and recommendation: The proportion of histologically analyzed parts of thernspecimen subjected is very low which probably resulted in the reduction in the incidence ofrnoverall incidental pathologic abnormalities in this study. Appropriate and complete histologicrnevaluation of each part of the specimens should be undertaken to get a base line data and helprnmake decisions in the future whether subjecting specimen for routine histopathological analysisrnafter vaginal hysterectomy should be practiced or not