Background: The HMIS is a tool which could be used to improve health services. Nations all over theworld are demanding to improve their healthcare service delivery quality through HMIS. Currently HMIS isrncoming up as one of the hot issues initiated to be reformed and implemented in Ethiopia. The purpose is tornrevitalize the health service provision through evidence-based decision-making. rnrnObjective: To assess the situation of Healthcare providers working in health centers of North Shoa Zone, rnOromia region in relation to HMISrn rnMethods: A cross-sectional survey was conducted among all 301 HCPs in Oromia region, North shoarnZone, in all health centers in March 2010.The quantitative data were collected using self- administeredrnbased pre-tested questionnaire. The study was consolidated with in-depth interview. EPI6 was used for datarnentry and cleaning and exported to SPSS version 16 statistical package for coding and analysis. Descriptivernanalysis was done to calculate the knowledge, attitude and practice scores. To show the association betweenrndependent and independent variables, odds ratio with 95% confidence interval was employed. Logisticrnregression analysis was done to control confounding effects amongst variables. rnrnResults: 296 questionnaires were returned making the response rate 98.3%. The overall knowledge and rnattitude on HMIS basic concept was found to be relatively good. But not seem to correspond with practicernas it is comparatively very low. About 70.61% of the respondents were found to have good knowledge. Thernfavorable attitude score was also found to be 81.08%. Concerning the practice, only 20.6% of thernrespondents were found to have good practice and significantly associated with unmarried marital statusrn[COR=3.22(95%CI=1.80, 5.75)] and [AOR=2.67(95%CI=1.28, 5.59)].From professional category, degreernholders had better practice of HMIS [COR= 2.93(95%CI=1.37,6.24)] and [AOR=2.93(95%CI=1.06,8.11)].rnAccording to the in-depth interview result, lack of trained and full time HMIS workers, unstandardized datarncollection and reporting tools were underlined as the main factors for malpracticing of HMIS at the healthrncenters. rn rnConclusion:rnAlthough the practice of HMIS neglected, the knowledge and attitude status of the HCPs onrnbasic HMIS concepts was relatively found to be good. As a result, the HMIS status in general was found tornbe very poor in the study area. rnrnRecommendation: Motivation and Training of HCPs on HMIS, provision of standardized data collection, rnand reporting tools, allocation of properly trained and full day HMIS workers with sustainable supportivernsupervision at each health centre were recommended to be given due consideration.