Sociodemographic Features Clinical Characteristics And Treatment Patterns Of Inflammatory Bowel Disease In Patients Seen At Tikur Anbessa Specialized Hospital (tash) During The Period Between January - August 2020 Addis Ababa
Background: Inflammatory bowel diseases (IBD) include ulcerative colitis (UC) and Crohn’s rndisease (CD). To date there are no reports from Ethiopia at a nationwide or hospital levels aboutrnthe epidemiology and clinical characteristics of IBD. rnObjective: To describe the sociodemographic features, clinical characteristics and treatmentrnpatterns of IBD in our patients.rnMethods and Materials: A descriptive study consisted of 102 patients who attended the GIrnreferral clinic in TASH from January - August 2020. Data was gathered through review of medicalrnrecords and patient interview; and a standardized questionnaire was applied. The collected datarnwas analyzed using SPSS v. 26. rnResults: A total of 102 IBD patients (29 UC, 73 CD and a ratio of 2.5:1) with femalernpredominance, 57% (n = 58) was identified. The M-to-F ratio was 1:1.2 for CD and 1:1.6 for UC.rnThe mean age at diagnosis was 26.4 years for CD and 33 years for UC. Only 5.9% of patients hadrna family history of IBD; and no association of smoking with IBD was found. EIMs were reportedrnin 16.6%. In patients with CD, the ileo-colon type was the most common disease phenotype (38%),rnand the inflammatory type was the most common disease behavior (49.3%); 18.6% ended up inrnbowel resection. In patients with UC, left-sided colitis was the predominant disease extent (69.0%).rnMajority of the patients were on steroids and immunomodulators. rnConclusions: There was a predominance of females in both IBD subtypes. CD was more commonrnthan UC, in comparison to what is mentioned in most literatures and the mean age at diagnosis wasrnin the mid-twenties for the former and early thirties for the later. None of the IBD patients wererntreated with biologic therapy.