Management Profile Of Rheumatoid Arthritis Patients At Tikur Anbessa Specialized Hospital Addis Ababa Ethiopia A Two- Year Retrospective Chart Review

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Background: Rheumatoid arthritis (RA), a chronic systemic inflammatory disease,rnpredominantly affects the joints, leading to functional disability and premature mortality.rnStandards of care have been established for its treatment. Its management include earlyrnaggressive, and persistent use of disease-modifying antirheumatic drugs (DMARDs) tornprevent joint damage in people with active inflammation. However, published evidence andrnguidance for its clinical management are lacking in resource limited countries such asrnEthiopia. This research assesses whether care for RA is consistent with current treatmentrnguidelines. rnObjective: To assess the management profile of RA patients who attended rheumatologyrnoutpatient care center of Tikur Anbessa Specialized Hospital (TASH), Addis Ababa, Ethiopiarnfrom January 1rnstrn, 2018 to December 31rnstrn, 2019. rnMethodology: A facility-based, cross-sectional study was conducted at rheumatologyrnoutpatient care center of TASH, Addis Ababa, Ethiopia. Data was collected using a structuredrnchecklist, and then entered and analyzed using SPSS version 26. Descriptive analysisrnemployed to identify the management gaps. Tables and figures were used to present thernresults. rnResults: The study evaluated medical records of 314 RA patients. Their age ranged from 18rnto 74 years with a median of 39.5 years and IQR of 30 to 51. Females dominated with arnfemale: male ratio of 5.4:1. RF was positive in 62.1% and anti-CCP was positive in 73.1% ofrnthe tested patients. Methotrexate was included in the regimen of most (93.6%) of the patientsrnand chloroquine in 67.2% of them. Overall, 48.7% were on combination therapy. And 85.4%rnwere subjected to steroids for more than six months. Baseline investigations were suboptimal.rnObjective measures of clinical remission were used in only 17.5% of the total. Successfulrnclinical remission was achieved in 75.8% of patients. Non-pharmacological treatments suchrnas physical therapy and psychological counseling were only delivered to 6.4% and 1% ofrnpatients, respectively. rnConclusion: Management gap of RA patients is a common observation in the study setting.rnThe most frequently observed management pitfalls are suboptimal use of DMARDs, use ofrnsteroids for extended duration, and underuse of non- pharmacological therapy such asrnphysical therapy and psychological support.

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Management Profile Of Rheumatoid Arthritis Patients At Tikur Anbessa Specialized Hospital Addis Ababa Ethiopia A Two-  Year Retrospective Chart Review

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