Prevalence Of Neurocognitive Impairment And Associated Factors Among Type-2 Diabetic Patients On Follow Up At Diabetic Clinic Tikur Anbessa Specialized Hospital Addis Ababa Ethiopia

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Background:-Neurocognitive disorders in patients with type 2 Diabetes Mellitus has spectrum rnmanifestation which might range from subtle executive dysfunction to memory loss and overt rndementia. Diabetes patients are at higher risk of all types of cognitive impairment, mainly rnbecause some diabetes complications results in cognitive impairments and they are also being rnconsidered as disease of the same spectrum. Even though it is estimated that more than 50 rnmillion peoples live with dementia worldwide, there is no enough data from low and middle rnincome countries, including Ethiopia, where the number is projected to increase to 152 million rnby 2050. Hence this study will focus on assessing the overall prevalence, potential determinant rnand contributing factors among patients with type 2 DM over a period of two months at Black rnLion Specialized Hospital, Ethiopia. rnObjective: - To assess the neurocognitive impairment and associated factors among diabetic rnpatients on follow up at diabetic clinic, Tikur Anbessa Specialized Hospital, Addis Ababa, rnEthiopia from July 1- August 30, 2021 rnMethods rnA hospital based Cross-sectional study was conducted on total of 338 type 2 diabetic patients on rnfollow-up at BLH. The sociodemographic, anthropometric and clinical data was collected by rntrained final year medical students. Both face to face interview and medical record reviews were rnused for data collection. A validated Mini Mental Status Examination tool was used to assess rncognitive impairment. Data was entered to epi-data cleared and analyzed by SPSS version 26.0. rnFinally, Descriptive analysis was carried out and presence of statistical association between rnneuro-cognitive impairment and associated factors was assessed using logistic regression and rnassociations with p-value of < 0.05 will be considered to be statistically significant. rnResults rnThe overall prevalence of neurocognitive impairment among type 2 diabetic patients on follow rnup at black lion specialized hospital was 38.75%. From Socio-demographic factors low rneducational level [AOR=3.65(1.855-7.188)] was associated with increased odds of encountering rncognitive impairments. While some clinical characteristics like being on oral hypoglycemic rnagents [AOR=0.786 (0.370-1.669)] or oral hypoglycemic agents combined with insulin rn[AOR=1.87(1.054-4.264) were associated with decreased likelihood of cognitive impairments. rnTotal duration of DM [(AOR=1.95(0.987-3.877)] and overall glycemic control [AOR= rn2.21(1.238-3.947)] had significant association with NCI. additionally coexisting hypertension rn[AOR= 0.53(0.314-0.918)] and presence of diabetic eye disease [AOR=1.84(1.056-3.229)] were rnalso associated with increased odds of encountering impairment. rnConclusion: - The finding indicated high prevalence of neurocognitive impairment among rnrespondents who had low level of education, prolonged duration of DM, poorly controlled DM, rndiabetic eye disease and coexisting hypertension.

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Prevalence Of Neurocognitive Impairment And  Associated Factors Among Type-2 Diabetic Patients On Follow Up At Diabetic Clinic Tikur  Anbessa Specialized Hospital Addis Ababa Ethiopia

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