Comparative Study On Changes In Hematological Parameters During The First 6 Month Of Antiretroviral Therapy Initiation Among Hiv Infected Pregnant And Non-pregnant Women At Zewditu Memorial Hospital Addis Ababa Ethiopia

Background: The use of ARV prophylaxis during pregnancy can dramatically reduce the risk ofrnvertical transmission of HIV infection. Currently, limited studies have documented the effect ofrnART in decreasing the risk of opportunistic infection as well as improving survival of HIVrninfected pregnant women and fetus. However, little is known about its impact on hematologicalrnparameters in resource limited settings like Ethiopia.rnObjective: To assess changes in hematological parameters after 6 months of ART initiationrnamong HIV infected pregnant and non-pregnant women at Zewditu Memorial Hospital ARTrnclinic, Addis Ababa, Ethiopia.rnMethodology: A retrospective comparative study was conducted among HIV infectedrnpregnant women who received ART between September 2008 and January 2014 at ARTrnclinic of Zewditu Memorial Hospital, Addis Ababa, Ethiopia. Data conveniently collected fromrn384 pregnant women on ART was compared with that obtained from 384 non pregnant womenrnwho are on ART as controls. Demographic, clinical and hematological parameters data wererncollected between November and December 2016 carefully from the existing ART logbook andrnantenatal follow up cards. Data collected through a standardized format were entered intornExcel spread sheet and transported into and analyzed by SPSS Version 20 software.rnDependent variable frequencies, mean, standard deviation and range were calculated. Meanrnchange of different hematological values during follow up time from the base line wererncompared using paired t-test. P value

Get Full Work

Report copyright infringement or plagiarism