Assessements Of Protein Energy Wasting In Patients With Chronic Kidney Disease Attending Renal Unit At Tikur Anbesa Specialized Hospital

Background: - Protein energy wasting (PEW) is highly prevalent in patients with chronic kidneyrndisease (CKD) and is a strong predictor of morbidity and mortality. Although data concerningrnthe prevalence of PEW in CKD are scarce in Ethiopia, it is hypothesized that there would berncomparable numbers of CKD patients with PEW in the country.rnObjectives: - The aim of the study was to assess protein energy wasting in patients with chronicrnkidney disease attending Renal unit at Tikur Anbesa Specialized Hospital.rnMethodology: - A cross sectional study design was conducted on 125 subjects at Tikur AnbessarnSpecialized Hospital. Out of the total, 85 were CKD patients and 40 were controls. Based onrntheir GFR values, CKD patients were further divided in to three groups. Group-I (n= 39) (GFRrn30-60 ml/min/1.73m2), Group-II (n=28) (GFR 15-29 ml/min/1.73m2) and Group-III (n=19)rn(GFR 10% > 6 months (47.4%) and s-albumin below the reference of 3.8g/dl (42.1%) were alsornin Group-III patients. GFR was found to be strongly correlated with s-albumin, BMI, andrnMAMC; while negatively correlated with unintentional weight loss.rnConclusion: The prevalence of protein energy wasting increased with advancing stage of CKD.rnBiochemical and anthropometric parameters deteriorated as kidney function decreased.rnKey words: Chronic kidney disease, Protein energy wasting, Mid Arm Muscle Circumference,rnBody mass index, Unintentional weight loss, serum albumin

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