Back ground: The occupational hazards such as dust and unfavorable microclimatic conditionsrninfluence human health. The occupation related lung diseases are most likely due to therndeposition of dust in the lungs, which is influenced by the types of dusts, the period of exposure,rnthe concentration and size of airborne dust in the breathing zone.rnObjective: To assess pulmonary function status in workers of flour mill in Addis Ababa,rnEthiopia.rnMethods: The study design was comparative cross sectional and the sampling technique wasrnconvenient sampling. A total of 54 flour mill workers who work for more than eight hours shiftrnper day and 54 control subjects matched for sex, age, weight, height and area of residence werernenrolled. Anthropometric measurements was done. Respiratory symptoms were evaluated usingrnstructured questionnaire (BMRC) guidelines and administered through face-to-face interview.rnLung function was measured using a digital portable spirometer (Spiro Pro) based on the ATSrnguidelines. FVC, FEV1, FEV1 %, PEFR and FEF25-75 %, were measured.rnResult: The present study showed statistically significant reduction in the mean values of PFTsrnin flour mill workers as compared to their matched controls. There also exist a dose responsernrelationship between impairment of lung function and duration of exposure. Percentagernprevalence of dry cough, productive cough; wheeze and breathlessness for exposed informantsrnwere much higher than control groups. Reductions in most PFTs in study subjects were veryrnsignificant for FVC (4.25±0.93 vs. 5.30±0.71, p