Pattern Of Fasting Blood Sugar Blood Pressure And Body Mass Index Among Combined Oral Contraceptive (coc) Pills Users In Chencha Southern Ethiopia.

Background: The use of contraceptives has become prevalent among women in Ethiopia. Oralrncontraceptive use has been suggested to trigger changes in glucose metabolism, energyrnexpenditure, blood pressure and body weight, among various population and ethnic groups.rnrnObjective: To elucidate the pattern of fasting blood sugar (FBS), blood pressure (BP) and bodyrnmass index (BMI) among combined oral contraceptive (COC) pills users, taking into accountrnother confounding factors including socioeconomic conditions, physical activity and nutritionalrnstatus. rnrnMethods: Institution based cross-sectional study design was employed. A total of 110 healthyrnwomen using COC pills were recruited as cases. Another 110 healthy women not using anyrnhormonal contraceptives were recruited as matched controls. A study was conducted betweenrnOctober 2018 and January 2019. Fasting Capillary blood samples were collected from the studyrnparticipants for the estimation of FBS level. Systolic and diastolic blood pressures werernmeasured. Body weight and height were measured to compute BMI. Data obtained was enteredrnand analyzed using IBM SPSS version 23 software packages.rnrnThe results: Fasting blood sugar level in COC users was significantly increased compared torncontrols (88.55±7.89 vs. 86.00±9.85 in users and controls respectively, P=0.036). There was arnsignificant difference in mean arterial blood pressure (MAP) of COC users compared to controlsrn(88.2±8.48 vs. 86.0±6.74 respectively, P=0.039). The mean weight and BMI of COC users werernincreased significantly (P =0.04 and P =0.004, respectively). Changes in mean FBS and weightrnof COC users were independent (P=0.27 and P=0.46) to the duration of use of COC (3-12, 13-24rnand ≥25 months). On the other hand, changes in mean BMI and MAP of COC users wererndependent on the duration of use (P=0.03 and P=0.000 respectively). rnrnConclusions: Overall, COC use appears to cause 2.9% increase in blood glucose level, 2.5% rnincrease in mean arterial blood pressure and 3.9% increase body mass index among users.

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