Gastrointestinal malignancies including esophageal, gastric, colorectal, hepatocellular, pancreatic andrngallbladder are responsible for more occurrence and more deaths than any other malignanciesrnworldwide. On the otherhand, positive as well as negative associations of serum lipids and lipoproteinsrnand glucose levels with different malignancies including gastrointestinal malignancy have beenrnreported by many researches.Thus, the main goal of this study was to find the association of glycemicrnlevel and lipid profile status of gastrointestinal malignant patients.This was done through hospitalrnbased crossÂsectional study in (70) GI malignant patients attending at Tikur Anbessa SpecializedrnHospital.The necessary data including serum fasting glucose and lipid proï¬le levels were alsorncollected and statistically analyzed and found the following results:The mean serum FGL was (107.81Ârnmg/dL) and (27.1%) IFG and (21.4%) hyperglycemic patients were found. Besides, significantlyrndifferent (p