Background: - Pregnancy-induced hypertension has remained a significant global public healthrnthreat in both developed and developing countries. Therefore, this study aims to assess renalrnfunction tests, serum total protein, lipid profile tests and associated risk factors among pregnantrnwomen with pregnancy-induced hypertension attending in Asrade Zewudie Memorable hospitalrn(ASZMPH), Gojjam, Ethiopia: Case-control study.rnMethods: - A prospective case control study was done from January 24, 2020, to April 30,rn2020. 200 pregnant women were recruited; 100rnwith pregnancy induced hypertension (case group) and 100 normotensives (control group). 5 mlrnof venous blood was collected on the SST test tube and analyzed for lipid profile, renal functionrnand serum total proten using standard enzymatic methods, modified Jaffe method, urease and biurnret method respectively. The analysis was done by using SPPS software (version 20.0). Finally,rnthe result was interpreted by using chi-square, Pearson's correlation, and multivariate logisticrnregression. The level of statistical significance was set at a 95% confidence interval and thosernvariables in which P-value is less than 0.05 were considered clinically significant. rnRESULTS:- In the present study, there was a significant increase in the serum level of serumrntotal cholesterol, triglyceride, blood urea, serum creatinine, and low density lipoprotein (p 0.05). Factors like body mass index (BMI) >24.9 k/mrn2rn, absence of scheduledrnexercise, alcohol, did not consume enough fruit, to be in the 3rnrdrn trimester and pregnant womenrnwith multigravidia status have significant association with abnormal results of lipid profile testsrnrelative with the reveres one. Factors like BMI >24.9 k/mrn2rn and multigravidia were havernsignificant association with blood urea nitrogen and serum creatinine test results. Also pregnantrnwomen's in the third trimester have more chance to have abnormally low serum total proteinrncompared with pregnant women in the second trimester in both groups(P< 0.05).rnCONCLUSION: - The findings of the present study indicated that abnormal results of lipidrnprofile and RFT were significantly associated with pregnancy induced hypertension. Alsornpregnant women's with body mass index >24.9 k/mrn2rn ,not doing scheduled exercise, drunksrnalcohol, not consuming fruit, in the 3rnrd rntrimester, and with multigravidia were have highrnsignificant chance to have abnormal results of lipid profile test, renal function test and serumrntotal protein relative with the opposite one. So it will better if clinicians use lipid profiles andrnrenal function tests as screening test than requesting other costly tests. Further studies in differentrnareas of the country by considering life style variation also recommended.