Sero-prevalence Of Hbsagamong Pregnant Women And Rate Of Vertical Transmission In Selected Health Facilities Of Addis Ababa Ethiopia

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Background: Pregnant women who are carriers of the HBV pose a significant risk to their healthrnandnewborn babies. Majority of countries in developing world have not yet adopted universalrnscreening for pregnant women.There are limited studies on maternal and their newborns HBVrnstatus in Ethiopia.rnObjective: - To determine the sero-prevalence of HBsAg among pregnant woman and rate ofrnvertical transmission in selected health facilities of Addis Ababa, EthiopiarnMethods: A prospective cross sectional studywasconductedat two hospitals from January– April,rn2018 G/C. Sociodemographic data were collected using pretested structured questionnaire.rnSerawere collected to determine the HBSAg usingImmunochromatographic test kitrnandconfirmation by ELISA. Data entry and analyseswere done using SPSS 20 statistical software.rnDescriptive statistics were used to summarize data. Proportions and the corresponding 95% CIrnwere presented. Mean and standard deviation wereused for numerical variables. Frequenciesrnwereused for categorical variables. Bivariate analysis was carried out to see association betweenrndependent and independent variables. P value of < 0.05 was considered significant associations.rnResults:A total of 420 samples from mothers and cord blood from newborns of positive mothersrnwere collected. Of these 404(96.2%) lived in rural part of the country, 87 % (357)and 58.6 %rn(246) were married and have primary level education, respectively.Government workersrnaccounted 20.7 % (87)of the study participants and 74.8% did not havehistory of bloodrntransfusion. In this study 3 % (13)of pregnant women were vaccinated and 14,5 % (61)were inrntheir first time pregnancy. Among 420 participants,2.38 % (10/420)were positive for HBV andrnno mother to child transmissionwas observed.rnConclusion:Although the low prevalence ratein this study concurs with what has beenrncategorized as intermediate endemicity and no vertical transmission is noted,every pregnantrnwoman should be testedfor HBV and check mother to child transmission.

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Sero-prevalence Of Hbsagamong Pregnant Women And Rate Of Vertical Transmission In Selected Health Facilities Of Addis Ababa Ethiopia

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