Assessment Of Blood Transfusion Utilization Patient Outcome Andassociated Factors At St. Paul Hospital Millennium Medical College Addis Ababa Ethiopia.

Background: Assessment of blood utilization is an important way to minimize unnecessary use rnof blood and blood components for transfusions so as to effectively manage such scarcernresources. However, in Ethiopia the regular assessment of transfusion practice is not performedrnconsistently. Regular audits are necessary to ensure blood and blood products are appropriate andrnclinical. rnObjective: To assess blood transfusion utilization , patient outcome and assocaited factors fromrnjuly 2020 to september 2020 at St, Paul’s Hospital Millennium Medical College. rnMethods: the utilization of blood, patient outcomes and associated factors were assessed in thisrnHospital based cross sectional study at St. Paul Hospital Millennium Medical College from Julyrnto September 2020. A standardized data extraction checklist was used to extract data from patientrnfile and from blood bank log book. Transfusion indices werecalculated. Data was entered andrnanalyzed using SPSS version 23. Dependent variable frequencies, percentage, mean and rangernwere calculated. The association between patient improvement and independent variables wasrnexamined using bivariate and multivariable logistic regression analysis. P-value less than 0.05rnwere considered as statistically significant and Odds ratios with 95% confidence interval werernused to determine strength of the association. rnResult: A total of 352 participants were included in the study. The majority of the patients werernfemale 218 (61.9%). The median and interquartile range [IQR] age of study participant was 30rn[20-43] years. For 352 study subjects, 1060 unit of blood components were transfused with thernmean of 3.01units per patient. From 1242 cross matched units, 85.3% wereutilized, the rest 14.7%rnwere returned to laboratory stock.Anemia was the commonest indication for transfusion andrnconcentrated red cell was the major component transfused. The study revealed the number ofrnunits cross matched/transfused (C|T) ratio of 1.17, Transfusion probability (%T) of 61.3%, andrnTransfusion index (TI) of 1.84. Only 177(50.3%) of the patients showed improvement. Patients inrnthe age group 1 to 10 years were more than 6 times more likely to improve than those aged underrnone year’sAOR and 95% CI =6.037[1.205-30.251], p=0.029. rnConclusion: The study demonstrated an encouraging rate of transfusion utilization in whichrn85.3% of cross matched blood is utilized. Transfusion indices,C/T, %T and TI, values were withinrnthe acceptable standard. The high rate of non-improvement warrants further investigation.

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