Assessment Of The Relationship Between Some Hematological Parameters And Blood Glucose Level And Its Role As Predictors Of Glycemic Control Among Diabetes Mellitus Patients Attending At Alert Hospital Addis Ababa Ethiopia

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Introduction: Good glycemic control is the main recommendation to prevent therndevelopment of diabetic complications. Recently, hematological parameters becamernrenewed interest in the clinical diagnosis and management of diabetes mellitus. rnObjective: the objective of this study was to assess selected hematological parameters asrnpredictors of glycemic control and its correlation with blood glucose level amongrndiabetes mellitus patients at ALERT hospital, Addis Ababa, Ethiopia. rnMethods: A cross-sectional study was conducted between February to August, 2020rnamong 422 diabetic patients attending at ALERT hospital to assess the utility of selectedrnhematological parameters as indicators of glycemic control association with FBS.rnDiabetic patients fulfilling the inclusion criteria were selected using convenient samplingrntechnique. Cell-Dyn Ruby and Cobasc331 analyzer were used. Data were analyzed usingrnSPSS version 25 and Chi-square test was used to assess association of dependent andrnindependent variables. ROC was employed to evaluate the utility of hematologicalrnparameters for glycemic control. rnResult: Of the 422diabetic patients enrolled in the study, 242(57.4%) were females andrn180 (42.6%) were males. ROC analysis result for MCH (AUC=0.647 (95% CI=0.5750.719)),rnrnHCT(AUC=0.599 (95% CI=0.508-0.689)), and MCV(AUC=0.662 (95%rnCI=0.588-0.736)), cut points were >29.55pg, >45.05%, and >90.25fl for MCH, HCT, andrnMCV, respectively.HCT(r=0.15), MCV(r=0.189),and RDW (r=0.156) showed positiverncorrelation with HbA1C. Correlation of hematological parameters with FBS indicatedrnthat RBC (r=0.147), HCT(r=0.112), and MPV (r=0.134) showed positive correlation withrnFBS. rnConclusion: HCT, RDW, MCH, and MCV had positive correlation with HbA1C;rnwhereas, RBC, Hb, HCT, and MPV had positive correlation with FBS. HCT, MCV andrnMCH are identified as the most sensitive and specific predictors for glycemic control.

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Assessment Of The Relationship Between Some Hematological Parameters And Blood Glucose Level And Its Role As Predictors Of Glycemic Control Among Diabetes Mellitus Patients Attending At Alert Hospital Addis Ababa Ethiopia

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