Background: - Managing HI V/ADIS & TB l aboratory c ommodities t hrough IPLS i s c rucial, t ornenhance s mooth c ommodities f low a nd pr event f requent s tock out of c ritical i tems w hich m ightrnhindering continuous and quality testing.rnObjective: - To assess implementation status of Integrated Pharmaceutical rnLogistics System (IPLS) forrnConclusion:- Majority o f th e f acilities r eported th e a vailability and u tilization o frnIPLSrnimplementation t ools for m anaging HIV/AIDS and TB l aboratory commodities, t hough 24( 96%) ofrnfacilities experienced stocked out for HIV/AIDs and TB laboratory commodities in the last six months,rnwhich provide in part an indication of failure to implement IPLS in full scales.rnKey words: - IPLS implementation, stock out, management supportrnrnmanaging HIV/ AIDS & TB laboratory diagnostics commoditiesrnMethods: - A cross-sectional descriptive study was conducted on 33 public health facilities in AddisrnAbaba. Information on characteristics of the selected facilities and indicators of IPLS implementationrn(measured u sing a vailabilities a nd u tilization o f IPLS to ols) w ere co llected u sing s tructuredrnquestionnaires c ustomized f orm Logistics Indicator A ssessment T ool ( LIAT). In a ddition, i n-depthrninterviews w ith k ey in formant w ere d one to e xtract in formation w hich was d ifficult to o btain u singrnquantitative m ethod. D ata obt ained t hrough s tructured q uestionnaires were en tered t o Excel s preadrnsheet an d t ransported a nd an alyzed u sing t he Statistical P ackage f or t he S ocial S ciences v ersion 2 0rn(SPSS). Results from the in-depth interview were summarized in narrative format.rnResult:-A t otal of 33 p ublic he alth f acilities w ere i nvolved i n t his s urvey. Of t hese 6( 18.1%) werernhospitals a nd 17( 51.5%) he alth center. A vailabilities ofrnIPLS recording and r eporting f ormatsrn(bincards, and IFRR and RRF) were reported in 92.6% of facilities. Of these 16(61.5%) of the facilitiesrnupdated bi ncard, 22( 84.6%) c ompleted IFRR a nd 24( 92.6%) r eported RRF f or H IV/AIDS and T Brnlaboratory commodities. Majority of the facilities (88.5%) facilities reported RRF report was submittedrnto PFSA every two month. 24(96%) of facilities were reported one or more reagents stocked out duringrnthe last six months. Of these (33.3%) of Clinical chemistry reagents were the most frequent stocked outrnreagents. 10(41.6%), 12(54.5%) and 11(46.7%) of facilities were stock out on day of visits for SGPT,rnBD va cationer E DTA t est t ube a nd 1% C arbol F uchsin r espectively w hile 7( 43.8%), 9( 64.7%) a ndrn9(69.8%) of facilities were stock out for SGOT, SGPT and 3% Acid alcohol during the last six monthsrnrespectively. Furthermore, management supports on IPLS implementation were significantly associatedrnwith acceptable data quality (X2= 22.2, p< 0.00) and utilization of IFRR (X2 = 5.71, p